Current status and prospects of traditional Chinese medicine combined with stem cell therapy for chronic kidney disease

Renal fibrosis is one of the main pathological features of chronic kidney disease (CKD), and its treatment has been a hot research topic. Recent studies have shown that stem cell therapy can repair renal pathological changes and slow the progression of CKD. In addition, a large number of experiments...

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Main Authors: Tianyang Qian, Yining He, Chao Han, Ruxue Yan, Weiming He
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Pharmacology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1505206/full
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author Tianyang Qian
Tianyang Qian
Yining He
Yining He
Chao Han
Chao Han
Ruxue Yan
Ruxue Yan
Weiming He
author_facet Tianyang Qian
Tianyang Qian
Yining He
Yining He
Chao Han
Chao Han
Ruxue Yan
Ruxue Yan
Weiming He
author_sort Tianyang Qian
collection DOAJ
description Renal fibrosis is one of the main pathological features of chronic kidney disease (CKD), and its treatment has been a hot research topic. Recent studies have shown that stem cell therapy can repair renal pathological changes and slow the progression of CKD. In addition, a large number of experiments have confirmed that traditional Chinese medicine (TCM), especially Chinese medicine compound preparations, has the advantage of multitargeting interventions to improve renal fibrosis. Therefore, stem cell therapy combined with TCM is expected to provide new therapeutic ideas and measures to solve kidney problems. This article reviews the current status of TCM combined with stem cell therapy for CKD, discusses existing problems, and proposes future prospects.
format Article
id doaj-art-d50219502ebf41f1b29d4e1c1a519974
institution Kabale University
issn 1663-9812
language English
publishDate 2025-01-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Pharmacology
spelling doaj-art-d50219502ebf41f1b29d4e1c1a5199742025-01-14T06:10:37ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122025-01-011510.3389/fphar.2024.15052061505206Current status and prospects of traditional Chinese medicine combined with stem cell therapy for chronic kidney diseaseTianyang Qian0Tianyang Qian1Yining He2Yining He3Chao Han4Chao Han5Ruxue Yan6Ruxue Yan7Weiming He8Division of Nephrology, Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing, ChinaThe First School of Clinical Medicine, Nanjing University of Chinese Medicine, Nanjing, ChinaDivision of Nephrology, Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing, ChinaThe First School of Clinical Medicine, Nanjing University of Chinese Medicine, Nanjing, ChinaThe First School of Clinical Medicine, Nanjing University of Chinese Medicine, Nanjing, ChinaYancheng Dafeng Hospital of Chinese Medicine, Teaching Hospital of Nanjing University of Chinese Medicine, Yancheng, ChinaDivision of Nephrology, Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing, ChinaThe First School of Clinical Medicine, Nanjing University of Chinese Medicine, Nanjing, ChinaDivision of Nephrology, Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing, ChinaRenal fibrosis is one of the main pathological features of chronic kidney disease (CKD), and its treatment has been a hot research topic. Recent studies have shown that stem cell therapy can repair renal pathological changes and slow the progression of CKD. In addition, a large number of experiments have confirmed that traditional Chinese medicine (TCM), especially Chinese medicine compound preparations, has the advantage of multitargeting interventions to improve renal fibrosis. Therefore, stem cell therapy combined with TCM is expected to provide new therapeutic ideas and measures to solve kidney problems. This article reviews the current status of TCM combined with stem cell therapy for CKD, discusses existing problems, and proposes future prospects.https://www.frontiersin.org/articles/10.3389/fphar.2024.1505206/fullstem cellstraditional Chinese medicinerenal fibrosischronic kidney diseasetreatment
spellingShingle Tianyang Qian
Tianyang Qian
Yining He
Yining He
Chao Han
Chao Han
Ruxue Yan
Ruxue Yan
Weiming He
Current status and prospects of traditional Chinese medicine combined with stem cell therapy for chronic kidney disease
Frontiers in Pharmacology
stem cells
traditional Chinese medicine
renal fibrosis
chronic kidney disease
treatment
title Current status and prospects of traditional Chinese medicine combined with stem cell therapy for chronic kidney disease
title_full Current status and prospects of traditional Chinese medicine combined with stem cell therapy for chronic kidney disease
title_fullStr Current status and prospects of traditional Chinese medicine combined with stem cell therapy for chronic kidney disease
title_full_unstemmed Current status and prospects of traditional Chinese medicine combined with stem cell therapy for chronic kidney disease
title_short Current status and prospects of traditional Chinese medicine combined with stem cell therapy for chronic kidney disease
title_sort current status and prospects of traditional chinese medicine combined with stem cell therapy for chronic kidney disease
topic stem cells
traditional Chinese medicine
renal fibrosis
chronic kidney disease
treatment
url https://www.frontiersin.org/articles/10.3389/fphar.2024.1505206/full
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