Parishin B blocking TRIB3-AKT1 interaction inhibits breast cancer lung metastasis

Parishin B blocking TRIB3-AKT1 interaction inhibits breast cancer lung metastasis

BackgroundTRIB3 has been reported to mediate breast cancer (BC) proliferation and metastasis by interacting with AKT1, and blocking the interaction between TRIB3 and AKT1 can inhibit the progression of BC. Besides, inhibiting TRIB3 to turn “cold tumor” hot has also been proved to be an effective the...

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Bibliographic Details
Main Authors: Xiongtao Cheng, Jianguo Sun, Shouhong Chen, Nan Wang, Weijing Tang, Zijian Xia, Yuhong Shu, Shouhong Gao, Zhipeng Wang, Xinxia Wang, Rongzi Shao, Jianxiong Cao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Pharmacology
Subjects:
TRIB3-AKT1 interaction
breast cancer lung metastasis
Parishin B
Co-IP assay
RNA-seq
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1517708/full
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