Age-dependent ACE2/TMPRSS2 expression and SARS-CoV-2 household transmission in Gran Canaria.

Age-dependent ACE2/TMPRSS2 expression and SARS-CoV-2 household transmission in Gran Canaria.

<h4>Background</h4>This study aimed to assess whether the expression of ACE2 and TMPRSS2 is associated with susceptibility to and severity of COVID-19 across age groups. We also evaluated the role of children in household transmission of SARS-CoV-2.<h4>Methods</h4>We conducte...

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Main Authors: Jesús Poch-Páez, Yeray Nóvoa-Medina, Abián Montesdeoca-Melián, Araceli Hernández-Betancor, Francisco J Rodríguez-Esparragón, Svetlana Pavlovic-Nesic, Melisa Hernández-Febles, Jesús M González-Martín, Laura Cappiello, Valewska Wallis-Gómez, Joaquin Quiralte-Castillo, Alejandro Maján-Rodríguez, Martín Castillo De Vera, Maria T Angulo-Moreno, Augusto González-Pérez, Asunción Rodríguez, Zelidety Espinel-Padrón, Elisa M Canino-Calderín, Irina Manzano-Gracia, Elena Colino-Gil, Ana I Reyes Dominguez, Irina Moreno-Afonso, Raquel McLaughlin-García, Maria L Naranjo-Báez, Ana Bordes-Benitez, Isabel De Miguel-Martínez, Carlos Rodríguez-Gallego, Luis Peña-Quintana
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0329229
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