Effect of Baduanjin exercise on health and functional status in patients with chronic obstructive pulmonary disease: a community-based, cluster-randomized controlled trial

Abstract Baduanjin has been shown to be an effective method of exercise for promoting body function in patients with chronic obstructive pulmonary disease (COPD). However, this method is rarely used by rural doctors in rural communities. The aim of this study was to compare the therapeutic effects o...

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Main Authors: Yong Chen, Pan Zhang, Zongmei Dong, Yanan Zhu, Yanan Liu, Cheng Qiao, Ning Zhang, Yixue Jiang, Bi Chen
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:npj Primary Care Respiratory Medicine
Online Access:https://doi.org/10.1038/s41533-024-00400-y
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author Yong Chen
Pan Zhang
Zongmei Dong
Yanan Zhu
Yanan Liu
Cheng Qiao
Ning Zhang
Yixue Jiang
Bi Chen
author_facet Yong Chen
Pan Zhang
Zongmei Dong
Yanan Zhu
Yanan Liu
Cheng Qiao
Ning Zhang
Yixue Jiang
Bi Chen
author_sort Yong Chen
collection DOAJ
description Abstract Baduanjin has been shown to be an effective method of exercise for promoting body function in patients with chronic obstructive pulmonary disease (COPD). However, this method is rarely used by rural doctors in rural communities. The aim of this study was to compare the therapeutic effects of Baduanjin exercise with those of conventional pulmonary rehabilitation (CPR) implemented by rural doctors in patients with COPD. A total of 472 COPD patients from 18 village clinics were randomly allocated to the Baduanjin group (n = 158), CPR group (n = 154), or control group (n = 160). The Baduanjin group received six months of Baduanjin training, the CPR group received six months of rehabilitation training, and the control group received usual care. The primary outcomes were changes in health status, as measured by the COPD Assessment Test (CAT), and dyspnoea, as assessed via the modified Medical Research Council (mMRC) dyspnoea scale. The secondary outcomes included six-minute walking distance (6MWD) performance and anxiety and depression scores on the Hospital Anxiety and Depression Scale (HADS-A and HADS-D, respectively). Baseline data were collected before randomization, and outcomes were ascertained at the six-month follow-up by blinded assessors. After six months of training, compared with the control group, the Baduanjin group presented significant improvements in CAT scores (t = 5.121, P  <  0.001), mMRC scale scores (t = 5.719, P < 0.001), 6MWD performance (t = 12.608, P < 0.001), HADS-A scores (t = 6.210, P  < 0.001), and HADS-D scores (t = 2.945, P = 0.010). The CPR group also presented significant improvements in CAT scores (t = 4.725, P < 0.001), mMRC scale scores (t = 5.499, P < 0.001), 6MWD performance (t = 11.662, P < 0.001), HADS-A scores (t = 5.697, P < 0.001), and HADS-D scores (t = 2.671, P = 0.023). In contrast, the control group participants showed no significant changes in CAT scores (t = –0.252, P = 0.801), mMRC scale scores (t = –0.085, P = 0.932), 6MWD performance (t = –0.463, P = 0.644), HADS-A scores (t = –2.75, P = 0.783), or HADS-D scores (t = –0.281, P = 0.779). No adverse events were reported during the study. The positive effects of Baduanjin exercise on the subjective symptoms of COPD patients are similar to those of CPR. The trial was registered with the Chinese Clinical Trials Registry (reference: ChiCTR-TRC-12001958) (22/02/2012).
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spelling doaj-art-d4b5cb6ef2204e23b717826f47b1e1d12024-12-22T12:15:51ZengNature Portfolionpj Primary Care Respiratory Medicine2055-10102024-12-0134111010.1038/s41533-024-00400-yEffect of Baduanjin exercise on health and functional status in patients with chronic obstructive pulmonary disease: a community-based, cluster-randomized controlled trialYong Chen0Pan Zhang1Zongmei Dong2Yanan Zhu3Yanan Liu4Cheng Qiao5Ning Zhang6Yixue Jiang7Bi Chen8Department of Public Health Management, Third People’s Hospital of XuzhouDepartment of Control and Prevention of Chronic Non-communicable Diseases, Xuzhou Center for Disease Control and PreventionDepartment of Control and Prevention of Chronic Non-communicable Diseases, Xuzhou Center for Disease Control and PreventionDepartment of Pulmonary and Critical Care Medicine, Affiliated Hospital of Xuzhou Medical UniversityDepartment of Pulmonary and Critical Care Medicine, Affiliated Hospital of Xuzhou Medical UniversityDepartment of Control and Prevention of Chronic Non-communicable Diseases, Xuzhou Center for Disease Control and PreventionDepartment of Control and Prevention of Chronic Non-communicable Diseases, Xuzhou Center for Disease Control and PreventionDepartment of Control and Prevention of Chronic Non-communicable Diseases, Xuzhou Center for Disease Control and PreventionDepartment of Pulmonary and Critical Care Medicine, Affiliated Hospital of Xuzhou Medical UniversityAbstract Baduanjin has been shown to be an effective method of exercise for promoting body function in patients with chronic obstructive pulmonary disease (COPD). However, this method is rarely used by rural doctors in rural communities. The aim of this study was to compare the therapeutic effects of Baduanjin exercise with those of conventional pulmonary rehabilitation (CPR) implemented by rural doctors in patients with COPD. A total of 472 COPD patients from 18 village clinics were randomly allocated to the Baduanjin group (n = 158), CPR group (n = 154), or control group (n = 160). The Baduanjin group received six months of Baduanjin training, the CPR group received six months of rehabilitation training, and the control group received usual care. The primary outcomes were changes in health status, as measured by the COPD Assessment Test (CAT), and dyspnoea, as assessed via the modified Medical Research Council (mMRC) dyspnoea scale. The secondary outcomes included six-minute walking distance (6MWD) performance and anxiety and depression scores on the Hospital Anxiety and Depression Scale (HADS-A and HADS-D, respectively). Baseline data were collected before randomization, and outcomes were ascertained at the six-month follow-up by blinded assessors. After six months of training, compared with the control group, the Baduanjin group presented significant improvements in CAT scores (t = 5.121, P  <  0.001), mMRC scale scores (t = 5.719, P < 0.001), 6MWD performance (t = 12.608, P < 0.001), HADS-A scores (t = 6.210, P  < 0.001), and HADS-D scores (t = 2.945, P = 0.010). The CPR group also presented significant improvements in CAT scores (t = 4.725, P < 0.001), mMRC scale scores (t = 5.499, P < 0.001), 6MWD performance (t = 11.662, P < 0.001), HADS-A scores (t = 5.697, P < 0.001), and HADS-D scores (t = 2.671, P = 0.023). In contrast, the control group participants showed no significant changes in CAT scores (t = –0.252, P = 0.801), mMRC scale scores (t = –0.085, P = 0.932), 6MWD performance (t = –0.463, P = 0.644), HADS-A scores (t = –2.75, P = 0.783), or HADS-D scores (t = –0.281, P = 0.779). No adverse events were reported during the study. The positive effects of Baduanjin exercise on the subjective symptoms of COPD patients are similar to those of CPR. The trial was registered with the Chinese Clinical Trials Registry (reference: ChiCTR-TRC-12001958) (22/02/2012).https://doi.org/10.1038/s41533-024-00400-y
spellingShingle Yong Chen
Pan Zhang
Zongmei Dong
Yanan Zhu
Yanan Liu
Cheng Qiao
Ning Zhang
Yixue Jiang
Bi Chen
Effect of Baduanjin exercise on health and functional status in patients with chronic obstructive pulmonary disease: a community-based, cluster-randomized controlled trial
npj Primary Care Respiratory Medicine
title Effect of Baduanjin exercise on health and functional status in patients with chronic obstructive pulmonary disease: a community-based, cluster-randomized controlled trial
title_full Effect of Baduanjin exercise on health and functional status in patients with chronic obstructive pulmonary disease: a community-based, cluster-randomized controlled trial
title_fullStr Effect of Baduanjin exercise on health and functional status in patients with chronic obstructive pulmonary disease: a community-based, cluster-randomized controlled trial
title_full_unstemmed Effect of Baduanjin exercise on health and functional status in patients with chronic obstructive pulmonary disease: a community-based, cluster-randomized controlled trial
title_short Effect of Baduanjin exercise on health and functional status in patients with chronic obstructive pulmonary disease: a community-based, cluster-randomized controlled trial
title_sort effect of baduanjin exercise on health and functional status in patients with chronic obstructive pulmonary disease a community based cluster randomized controlled trial
url https://doi.org/10.1038/s41533-024-00400-y
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