Bioluminescent Pseudomonas aeruginosa and Escherichia coli for whole-cell screening of antibacterial and adjuvant compounds

Abstract Continued efforts to discover new antibacterial molecules are critical to achieve a robust pre-clinical pipeline for new antibiotics. Screening of compound or natural product extract libraries remains a widespread approach and can benefit from the development of whole cell assays that are r...

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Main Authors: Eszter Farkas, Geoffrey A. McKay, Lin Tao Hu, Mina Nekouei, Peying Ho, Wilfried Moreira, Chia Ching Chan, Linh Chi Dam, Karine Auclair, Samantha Gruenheid, Lyle Whyte, Peter Dedon, Dao Nguyen
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-81926-6
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