Associations between organic erectile dysfunction and the risk of herpes zoster and postherpetic neuralgia in men

Background Whether erectile dysfunction (ED) leads to considerable stress for affected men remains unclear? In this study, we investigated whether organic ED (OED) is associated with increased risks of herpes zoster (HZ) and postherpetic neuralgia (PHN).Methods A representative subset of Taiwan’s Na...

Full description

Saved in:
Bibliographic Details
Main Authors: Kuan-Hsun Wang, Wen-Che Hsieh, Heng-Jun Lin, Fuu-Jen Tsai, Chao-Yu Hsu
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:The Aging Male
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/13685538.2024.2346310
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1846143533365329920
author Kuan-Hsun Wang
Wen-Che Hsieh
Heng-Jun Lin
Fuu-Jen Tsai
Chao-Yu Hsu
author_facet Kuan-Hsun Wang
Wen-Che Hsieh
Heng-Jun Lin
Fuu-Jen Tsai
Chao-Yu Hsu
author_sort Kuan-Hsun Wang
collection DOAJ
description Background Whether erectile dysfunction (ED) leads to considerable stress for affected men remains unclear? In this study, we investigated whether organic ED (OED) is associated with increased risks of herpes zoster (HZ) and postherpetic neuralgia (PHN).Methods A representative subset of Taiwan’s National Health Insurance Research Database was employed for this study. Enrollees with OED from the years 2000 to 2018 were selected. To ensure comparability between the case and control groups, we implemented 1:1 propensity score matching based on age, index year, comorbidities, and medications.Results The case group included 20,808 patients with OED, while the control group consisted of 20,808 individuals without OED. The OED group exhibited a significantly elevated risk of HZ (adjusted hazard ratio [aHR] = 1.74) and PHN (aHR = 1.56) compared to the non-OED group.Conclusions Men experiencing OED seem to face elevated risks of HZ and PHN compared to those without OED. ED may serve as a warning sign for individuals at HZ risk.
format Article
id doaj-art-d428ffcb2fc84bd4a09c80d5450750ba
institution Kabale University
issn 1368-5538
1473-0790
language English
publishDate 2024-12-01
publisher Taylor & Francis Group
record_format Article
series The Aging Male
spelling doaj-art-d428ffcb2fc84bd4a09c80d5450750ba2024-12-02T12:17:12ZengTaylor & Francis GroupThe Aging Male1368-55381473-07902024-12-0127110.1080/13685538.2024.2346310Associations between organic erectile dysfunction and the risk of herpes zoster and postherpetic neuralgia in menKuan-Hsun Wang0Wen-Che Hsieh1Heng-Jun Lin2Fuu-Jen Tsai3Chao-Yu Hsu4Department of Family Medicine, Antai Medical Care Corporation Antai Tian-Sheng Memorial Hospital, Pingtung, TaiwanDepartment of Chinese Medicine, Ditmanson Medical Foundation, Chia-Yi Christian Hospital, Chia-Yi, TaiwanManagement Office for Health Data, Clinical Trial Research Center, China Medical University Hospital, Taichung, TaiwanSchool of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, TaiwanDepartment of Medical Education, Ditmanson Medical Foundation, Chia-Yi Christian Hospital, Chia-Yi, TaiwanBackground Whether erectile dysfunction (ED) leads to considerable stress for affected men remains unclear? In this study, we investigated whether organic ED (OED) is associated with increased risks of herpes zoster (HZ) and postherpetic neuralgia (PHN).Methods A representative subset of Taiwan’s National Health Insurance Research Database was employed for this study. Enrollees with OED from the years 2000 to 2018 were selected. To ensure comparability between the case and control groups, we implemented 1:1 propensity score matching based on age, index year, comorbidities, and medications.Results The case group included 20,808 patients with OED, while the control group consisted of 20,808 individuals without OED. The OED group exhibited a significantly elevated risk of HZ (adjusted hazard ratio [aHR] = 1.74) and PHN (aHR = 1.56) compared to the non-OED group.Conclusions Men experiencing OED seem to face elevated risks of HZ and PHN compared to those without OED. ED may serve as a warning sign for individuals at HZ risk.https://www.tandfonline.com/doi/10.1080/13685538.2024.2346310Erectile dysfunctionherpes zosterpostherpetic neuralgia
spellingShingle Kuan-Hsun Wang
Wen-Che Hsieh
Heng-Jun Lin
Fuu-Jen Tsai
Chao-Yu Hsu
Associations between organic erectile dysfunction and the risk of herpes zoster and postherpetic neuralgia in men
The Aging Male
Erectile dysfunction
herpes zoster
postherpetic neuralgia
title Associations between organic erectile dysfunction and the risk of herpes zoster and postherpetic neuralgia in men
title_full Associations between organic erectile dysfunction and the risk of herpes zoster and postherpetic neuralgia in men
title_fullStr Associations between organic erectile dysfunction and the risk of herpes zoster and postherpetic neuralgia in men
title_full_unstemmed Associations between organic erectile dysfunction and the risk of herpes zoster and postherpetic neuralgia in men
title_short Associations between organic erectile dysfunction and the risk of herpes zoster and postherpetic neuralgia in men
title_sort associations between organic erectile dysfunction and the risk of herpes zoster and postherpetic neuralgia in men
topic Erectile dysfunction
herpes zoster
postherpetic neuralgia
url https://www.tandfonline.com/doi/10.1080/13685538.2024.2346310
work_keys_str_mv AT kuanhsunwang associationsbetweenorganicerectiledysfunctionandtheriskofherpeszosterandpostherpeticneuralgiainmen
AT wenchehsieh associationsbetweenorganicerectiledysfunctionandtheriskofherpeszosterandpostherpeticneuralgiainmen
AT hengjunlin associationsbetweenorganicerectiledysfunctionandtheriskofherpeszosterandpostherpeticneuralgiainmen
AT fuujentsai associationsbetweenorganicerectiledysfunctionandtheriskofherpeszosterandpostherpeticneuralgiainmen
AT chaoyuhsu associationsbetweenorganicerectiledysfunctionandtheriskofherpeszosterandpostherpeticneuralgiainmen