Development of a Single Detector Ring Micro Crystal Element Scanner: QuickPET II

This article describes a single ring version of the micro crystal element scanner (MiCES) and investigation of its spatial resolution imaging characteristics for mouse positron emission tomography (PET) imaging. This single ring version of the MiCES system, referred to as QuickPET II, consists of 18...

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Main Authors: Robert S. Miyaoka, Marie L. Janes, Kisung Lee, Byungki Park, Paul E. Kinahan, Tom K. Lewellen
Format: Article
Language:English
Published: SAGE Publishing 2005-04-01
Series:Molecular Imaging
Online Access:https://doi.org/10.1162/15353500200504154
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author Robert S. Miyaoka
Marie L. Janes
Kisung Lee
Byungki Park
Paul E. Kinahan
Tom K. Lewellen
author_facet Robert S. Miyaoka
Marie L. Janes
Kisung Lee
Byungki Park
Paul E. Kinahan
Tom K. Lewellen
author_sort Robert S. Miyaoka
collection DOAJ
description This article describes a single ring version of the micro crystal element scanner (MiCES) and investigation of its spatial resolution imaging characteristics for mouse positron emission tomography (PET) imaging. This single ring version of the MiCES system, referred to as QuickPET II, consists of 18 MiCE detector modules mounted as a single ring in a vertical gantry. The system has a 5.76-cm transverse field of view and a 1.98-cm axial field of view. In addition to the scanner and data acquisition system, we have developed an iterative reconstruction that includes a model of the system's detector response function. Evaluation images of line sources and mice have been acquired. Using filtered backprojection, the resolution for a reconstructed line source has been measured at 1.2 mm full width at half maximum. F-18-2-fluoro-2-deoxyglucose mouse PET images are provided. The result shows that QuickPET II has the imaging characteristics to support high-resolution, static mouse PET studies using 18-F labeled compounds.
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institution Kabale University
issn 1536-0121
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publisher SAGE Publishing
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series Molecular Imaging
spelling doaj-art-d41f818e376f45e98e601d56e4ea24f02025-01-03T00:11:34ZengSAGE PublishingMolecular Imaging1536-01212005-04-01410.1162/1535350020050415410.1162_15353500200504154Development of a Single Detector Ring Micro Crystal Element Scanner: QuickPET IIRobert S. MiyaokaMarie L. JanesKisung LeeByungki ParkPaul E. KinahanTom K. LewellenThis article describes a single ring version of the micro crystal element scanner (MiCES) and investigation of its spatial resolution imaging characteristics for mouse positron emission tomography (PET) imaging. This single ring version of the MiCES system, referred to as QuickPET II, consists of 18 MiCE detector modules mounted as a single ring in a vertical gantry. The system has a 5.76-cm transverse field of view and a 1.98-cm axial field of view. In addition to the scanner and data acquisition system, we have developed an iterative reconstruction that includes a model of the system's detector response function. Evaluation images of line sources and mice have been acquired. Using filtered backprojection, the resolution for a reconstructed line source has been measured at 1.2 mm full width at half maximum. F-18-2-fluoro-2-deoxyglucose mouse PET images are provided. The result shows that QuickPET II has the imaging characteristics to support high-resolution, static mouse PET studies using 18-F labeled compounds.https://doi.org/10.1162/15353500200504154
spellingShingle Robert S. Miyaoka
Marie L. Janes
Kisung Lee
Byungki Park
Paul E. Kinahan
Tom K. Lewellen
Development of a Single Detector Ring Micro Crystal Element Scanner: QuickPET II
Molecular Imaging
title Development of a Single Detector Ring Micro Crystal Element Scanner: QuickPET II
title_full Development of a Single Detector Ring Micro Crystal Element Scanner: QuickPET II
title_fullStr Development of a Single Detector Ring Micro Crystal Element Scanner: QuickPET II
title_full_unstemmed Development of a Single Detector Ring Micro Crystal Element Scanner: QuickPET II
title_short Development of a Single Detector Ring Micro Crystal Element Scanner: QuickPET II
title_sort development of a single detector ring micro crystal element scanner quickpet ii
url https://doi.org/10.1162/15353500200504154
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