Normative values for retinal parameters in a Ghanaian clinical population at risk for glaucoma
Background: There is rarity of normative data on retinal parameters associated with glaucoma in Ghanaians. Aim: This study aimed to provide normative data on retinal parameters associated with glaucoma in an at-risk Ghanaian clinical population. Setting: The study was conducted at the Eye Clinic o...
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| Language: | English |
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AOSIS
2024-11-01
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| Series: | African Vision and Eye Health |
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| Online Access: | https://avehjournal.org/index.php/aveh/article/view/951 |
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| author | Doreen Nelson-Ayifah Khathutshelo P. Mashige Alvin J. Munsamy |
| author_facet | Doreen Nelson-Ayifah Khathutshelo P. Mashige Alvin J. Munsamy |
| author_sort | Doreen Nelson-Ayifah |
| collection | DOAJ |
| description | Background: There is rarity of normative data on retinal parameters associated with glaucoma in Ghanaians.
Aim: This study aimed to provide normative data on retinal parameters associated with glaucoma in an at-risk Ghanaian clinical population.
Setting: The study was conducted at the Eye Clinic of the Komfo Anokye Teaching Hospital, Ghana.
Methods: Ophthalmic data were obtained from 338 eyes of 116 males and 222 females (mean age: 61.86 ± 9.54 years, range: 45–89 years). The participants underwent eye examinations including visual acuity measurement using the Snellen chart at 6 m, auto-refraction using the Retinomax K+ Screen Hand-Held Autorefractor Keratometer, Goldmann applanation tonometry, slit-lamp biomicroscopy, fundus examination using a 90D Volks lens, and optical coherence tomography (OCT) using the Zeiss Cirrus HD OCT (Carl Zeiss Meditec, Dublin, CA, United States). Height and weight of participants were measured using a measuring tape and a weighing scale, respectively.
Results: Mean ± standard deviation values for retinal parameters were: global peripapillary retinal nerve fibre layer (ppRNFL) = 96.11 ± 9.87 µm, global macula ganglion cell complex (mGCC) = 80.91 ± 5.61 µm, optic disc area = 2.05 ± 0.39 mm2, rim area = 1.52 ± 0.27 mm2, cup volume = 0.13 ± 0.12 mm3, average cup to disc ratio (ACDR) = 0.47 ± 0.15 and vertical cup to disc ratio (VCDR) = 0.44 ± 0.14.
Conclusion: Thicker ppRNFL and mGCC may delay diagnosis of pre-perimetric glaucoma in Ghanaians, while larger ACDR and VCDR measurements may lead to glaucoma misdiagnosis.
Contribution: This study established normative values for retinal parameters associated with glaucoma in Ghanaians. |
| format | Article |
| id | doaj-art-d40203d06ecd491dbdc481b103c07fc3 |
| institution | Kabale University |
| issn | 2413-3183 2410-1516 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | AOSIS |
| record_format | Article |
| series | African Vision and Eye Health |
| spelling | doaj-art-d40203d06ecd491dbdc481b103c07fc32024-12-03T11:13:43ZengAOSISAfrican Vision and Eye Health2413-31832410-15162024-11-01831e1e910.4102/aveh.v83i1.951610Normative values for retinal parameters in a Ghanaian clinical population at risk for glaucomaDoreen Nelson-Ayifah0Khathutshelo P. Mashige1Alvin J. Munsamy2Discipline of Optometry, School of Health Sciences, University of KwaZulu-Natal, Durban, South Africa; and Kumasi Centre for Collaborative Research in Tropical Medicine, Kwame Nkrumah University of Science and Technology, KumasiDiscipline of Optometry, School of Health Sciences, University of KwaZulu-Natal, DurbanDiscipline of Optometry, School of Health Sciences, University of KwaZulu-Natal, DurbanBackground: There is rarity of normative data on retinal parameters associated with glaucoma in Ghanaians. Aim: This study aimed to provide normative data on retinal parameters associated with glaucoma in an at-risk Ghanaian clinical population. Setting: The study was conducted at the Eye Clinic of the Komfo Anokye Teaching Hospital, Ghana. Methods: Ophthalmic data were obtained from 338 eyes of 116 males and 222 females (mean age: 61.86 ± 9.54 years, range: 45–89 years). The participants underwent eye examinations including visual acuity measurement using the Snellen chart at 6 m, auto-refraction using the Retinomax K+ Screen Hand-Held Autorefractor Keratometer, Goldmann applanation tonometry, slit-lamp biomicroscopy, fundus examination using a 90D Volks lens, and optical coherence tomography (OCT) using the Zeiss Cirrus HD OCT (Carl Zeiss Meditec, Dublin, CA, United States). Height and weight of participants were measured using a measuring tape and a weighing scale, respectively. Results: Mean ± standard deviation values for retinal parameters were: global peripapillary retinal nerve fibre layer (ppRNFL) = 96.11 ± 9.87 µm, global macula ganglion cell complex (mGCC) = 80.91 ± 5.61 µm, optic disc area = 2.05 ± 0.39 mm2, rim area = 1.52 ± 0.27 mm2, cup volume = 0.13 ± 0.12 mm3, average cup to disc ratio (ACDR) = 0.47 ± 0.15 and vertical cup to disc ratio (VCDR) = 0.44 ± 0.14. Conclusion: Thicker ppRNFL and mGCC may delay diagnosis of pre-perimetric glaucoma in Ghanaians, while larger ACDR and VCDR measurements may lead to glaucoma misdiagnosis. Contribution: This study established normative values for retinal parameters associated with glaucoma in Ghanaians.https://avehjournal.org/index.php/aveh/article/view/951glaucomaafricansnormative databaseghanaretinaoptic nerve |
| spellingShingle | Doreen Nelson-Ayifah Khathutshelo P. Mashige Alvin J. Munsamy Normative values for retinal parameters in a Ghanaian clinical population at risk for glaucoma African Vision and Eye Health glaucoma africans normative database ghana retina optic nerve |
| title | Normative values for retinal parameters in a Ghanaian clinical population at risk for glaucoma |
| title_full | Normative values for retinal parameters in a Ghanaian clinical population at risk for glaucoma |
| title_fullStr | Normative values for retinal parameters in a Ghanaian clinical population at risk for glaucoma |
| title_full_unstemmed | Normative values for retinal parameters in a Ghanaian clinical population at risk for glaucoma |
| title_short | Normative values for retinal parameters in a Ghanaian clinical population at risk for glaucoma |
| title_sort | normative values for retinal parameters in a ghanaian clinical population at risk for glaucoma |
| topic | glaucoma africans normative database ghana retina optic nerve |
| url | https://avehjournal.org/index.php/aveh/article/view/951 |
| work_keys_str_mv | AT doreennelsonayifah normativevaluesforretinalparametersinaghanaianclinicalpopulationatriskforglaucoma AT khathutshelopmashige normativevaluesforretinalparametersinaghanaianclinicalpopulationatriskforglaucoma AT alvinjmunsamy normativevaluesforretinalparametersinaghanaianclinicalpopulationatriskforglaucoma |