ACTN1 promotes cell invasion, migration, and EMT in thyroid cancer and is associated with immune infiltration

ACTN1 promotes cell invasion, migration, and EMT in thyroid cancer and is associated with immune infiltration

Abstract Alpha-actin-1 (ACTN1) is a cytoskeletal protein, and new evidence suggests that it is associated with tumor progression and prognosis. However, the expression of ACTN1 in thyroid carcinoma (THCA) and its biological functions are not fully understood. This study aimed to explore the expressi...

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Bibliographic Details
Main Authors: Song Chen, Xue Luo, Wentai Wang, Xing-hong Chen, Ning Ma, Xue-yin Zhu, Tian Zhou, Qing-jun Gao, Dai-wei Zhao
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
Thyroid cancer
ACTN1
Tumour immunity
Epithelial‒mesenchymal transition (EMT)
Tumour metastasis
Aggressive subtypes
Online Access:https://doi.org/10.1038/s41598-024-83719-3
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