The methyltransferase SETD3 regulates mRNA alternative splicing through interacting with hnRNPK

The methyltransferase SETD3 regulates mRNA alternative splicing through interacting with hnRNPK

The methyltransferase SETD3 is an enzyme essential for catalyzing histidine-73 methylation on β-Actin, thereby promoting its polymerization and regulating muscle contraction. Although increasing evidence suggests that SETD3 is involved in multiple physiological or pathological events, its biological...

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Bibliographic Details
Main Authors: Yue-Yu Kong, Wen-Jie Shu, Shuang Wang, Zhao-Hong Yin, Hongguo Duan, Ke Li, Hai-Ning Du
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Cell Insight
Subjects:
SETD3
RNA splicing
RBPs
hnRNPK
FNIP1
Online Access:http://www.sciencedirect.com/science/article/pii/S2772892724000531
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