In Vivo Testing of Luciferase Substrate Analogs in an Orthotopic Murine Model of Human Glioblastoma

In vivo bioluminescent imaging using cells expressing Renilla luciferase is becoming increasingly common. Hindrances to the more widespread use of Renilla luciferase are the high autoluminescence of its natural substrate, coelenterazine, in plasma; the relatively high absorbance by tissue of the lig...

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Bibliographic Details
Main Authors: Maya Otto-Duessel, Vazgen Khankaldyyan, Ignacio Gonzalez-Gomez, Michael C. Jensen, Walter E. Laug, Michael Rosol
Format: Article
Language:English
Published: SAGE Publishing 2006-04-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2006.00006
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