Miao medicine Tiekuaizi (Radix Chimonanthi): a review of its traditional uses, phytochemistry, pharmacology, and predictive analysis on quality markers
Miao medicine Tiekuaizi (Radix Chimonanthi) has been successfully used by Guizhou Miao ethnic physicians in clinical treatments, demonstrating significant curative effects. The research progress on the resource distribution, traditional uses, phytochemistry, and pharmacology of Tiekuaizi was reviewe...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Pharmacology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2024.1491585/full |
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| author | Li-ying Luo Xu-dong Zhang Hui-min Mei Jian-hui Ma Xin Peng Ming-hong Dong Cong Huang Cong Huang |
| author_facet | Li-ying Luo Xu-dong Zhang Hui-min Mei Jian-hui Ma Xin Peng Ming-hong Dong Cong Huang Cong Huang |
| author_sort | Li-ying Luo |
| collection | DOAJ |
| description | Miao medicine Tiekuaizi (Radix Chimonanthi) has been successfully used by Guizhou Miao ethnic physicians in clinical treatments, demonstrating significant curative effects. The research progress on the resource distribution, traditional uses, phytochemistry, and pharmacology of Tiekuaizi was reviewed by collecting related literature from traditional Chinese medicine books and various databases. Based on the comprehensive review and centered around the principles of traditional Chinese medicine quality marker (Q-Marker) theory, nine secondary metabolites (scopoletin, scopolin, isofraxidin, fraxin, scoparone, calycanthoside, 6, 7, 8-trimethoxycoumarin, tomenin, and calycanthine) are suggested as potential Q-markers for Tiekuaizi to establish quality control standards. This can provide a valuable reference for the collection and processing, pharmaceutical production, and effectiveness and safety of clinical applications of Miao medicine Tiekuaizi. |
| format | Article |
| id | doaj-art-d37daaf1b0f944ea86e6b9afa476f2a9 |
| institution | Kabale University |
| issn | 1663-9812 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj-art-d37daaf1b0f944ea86e6b9afa476f2a92025-01-03T04:12:05ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122025-01-011510.3389/fphar.2024.14915851491585Miao medicine Tiekuaizi (Radix Chimonanthi): a review of its traditional uses, phytochemistry, pharmacology, and predictive analysis on quality markersLi-ying Luo0Xu-dong Zhang1Hui-min Mei2Jian-hui Ma3Xin Peng4Ming-hong Dong5Cong Huang6Cong Huang7Guizhou University of Traditional Chinese Medicine, Guiyang, ChinaGuizhou University of Traditional Chinese Medicine, Guiyang, ChinaGuizhou University of Traditional Chinese Medicine, Guiyang, ChinaGuizhou University of Traditional Chinese Medicine, Guiyang, ChinaGuizhou University of Traditional Chinese Medicine, Guiyang, ChinaGuizhou University of Traditional Chinese Medicine, Guiyang, ChinaGuizhou University of Traditional Chinese Medicine, Guiyang, ChinaAnshun Hospital of Traditional Chinese Medicine, Anshun, ChinaMiao medicine Tiekuaizi (Radix Chimonanthi) has been successfully used by Guizhou Miao ethnic physicians in clinical treatments, demonstrating significant curative effects. The research progress on the resource distribution, traditional uses, phytochemistry, and pharmacology of Tiekuaizi was reviewed by collecting related literature from traditional Chinese medicine books and various databases. Based on the comprehensive review and centered around the principles of traditional Chinese medicine quality marker (Q-Marker) theory, nine secondary metabolites (scopoletin, scopolin, isofraxidin, fraxin, scoparone, calycanthoside, 6, 7, 8-trimethoxycoumarin, tomenin, and calycanthine) are suggested as potential Q-markers for Tiekuaizi to establish quality control standards. This can provide a valuable reference for the collection and processing, pharmaceutical production, and effectiveness and safety of clinical applications of Miao medicine Tiekuaizi.https://www.frontiersin.org/articles/10.3389/fphar.2024.1491585/fullMiao medicine TiekuaiziRadix Chimonanthiphytochemistrypharmacologyquality marker |
| spellingShingle | Li-ying Luo Xu-dong Zhang Hui-min Mei Jian-hui Ma Xin Peng Ming-hong Dong Cong Huang Cong Huang Miao medicine Tiekuaizi (Radix Chimonanthi): a review of its traditional uses, phytochemistry, pharmacology, and predictive analysis on quality markers Frontiers in Pharmacology Miao medicine Tiekuaizi Radix Chimonanthi phytochemistry pharmacology quality marker |
| title | Miao medicine Tiekuaizi (Radix Chimonanthi): a review of its traditional uses, phytochemistry, pharmacology, and predictive analysis on quality markers |
| title_full | Miao medicine Tiekuaizi (Radix Chimonanthi): a review of its traditional uses, phytochemistry, pharmacology, and predictive analysis on quality markers |
| title_fullStr | Miao medicine Tiekuaizi (Radix Chimonanthi): a review of its traditional uses, phytochemistry, pharmacology, and predictive analysis on quality markers |
| title_full_unstemmed | Miao medicine Tiekuaizi (Radix Chimonanthi): a review of its traditional uses, phytochemistry, pharmacology, and predictive analysis on quality markers |
| title_short | Miao medicine Tiekuaizi (Radix Chimonanthi): a review of its traditional uses, phytochemistry, pharmacology, and predictive analysis on quality markers |
| title_sort | miao medicine tiekuaizi radix chimonanthi a review of its traditional uses phytochemistry pharmacology and predictive analysis on quality markers |
| topic | Miao medicine Tiekuaizi Radix Chimonanthi phytochemistry pharmacology quality marker |
| url | https://www.frontiersin.org/articles/10.3389/fphar.2024.1491585/full |
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