Desmoplastic Ameloblastoma: A case report of rare pulmonary metastasis
Pulmonary metastasis of ameloblastoma is a rare associated with the histopathologically plexiform types of ameloblastoma. In this report, we present an exceptionally rare case of pulmonary metastatic ameloblastoma without local recurrence, emerging 12 years post-initial resection. A female patient,...
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| Language: | English |
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Elsevier
2024-12-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024165668 |
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| author | Takaaki Kamatani Ryogo Katada Masataka Watanabe Tatsuo Shirota |
| author_facet | Takaaki Kamatani Ryogo Katada Masataka Watanabe Tatsuo Shirota |
| author_sort | Takaaki Kamatani |
| collection | DOAJ |
| description | Pulmonary metastasis of ameloblastoma is a rare associated with the histopathologically plexiform types of ameloblastoma. In this report, we present an exceptionally rare case of pulmonary metastatic ameloblastoma without local recurrence, emerging 12 years post-initial resection. A female patient, initially diagnosed with mandibular desmoplastic ameloblastoma, revealed masses in both lung fields of the lung on chest radiography, while chest computed tomography revealed more than 10 nodules in both lungs. Histopathological analysis of a lung biopsy specimen revealed a nest-like structure of tumor cells surrounded by highly columnar cells, exhibiting a palisade-like arrangement, and squamous metaplasia.Subsequently, the diagnosis of pulmonary metastatic ameloblastoma was confirmed through immunohistochemical examination. Despite clinical trial treatment with molecular targeted therapy for three years, the lung disease remained clinically stable. This case highlights the need for oral surgeons to recognize that pulmonary metastasis of desmoplastic ameloblastoma can manifest as a late recurrence, extending beyond a decade after initial curative surgery. |
| format | Article |
| id | doaj-art-d37b68c274704fa9b8096c3d295a66b8 |
| institution | Kabale University |
| issn | 2405-8440 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj-art-d37b68c274704fa9b8096c3d295a66b82024-12-13T10:58:57ZengElsevierHeliyon2405-84402024-12-011023e40535Desmoplastic Ameloblastoma: A case report of rare pulmonary metastasisTakaaki Kamatani0Ryogo Katada1Masataka Watanabe2Tatsuo Shirota3Corresponding author.; Department of Oral and Maxillofacial Surgery, Showa University School of Dentistry, Tokyo 145-8515, JapanDepartment of Oral and Maxillofacial Surgery, Showa University School of Dentistry, Tokyo 145-8515, JapanDepartment of Oral and Maxillofacial Surgery, Showa University School of Dentistry, Tokyo 145-8515, JapanDepartment of Oral and Maxillofacial Surgery, Showa University School of Dentistry, Tokyo 145-8515, JapanPulmonary metastasis of ameloblastoma is a rare associated with the histopathologically plexiform types of ameloblastoma. In this report, we present an exceptionally rare case of pulmonary metastatic ameloblastoma without local recurrence, emerging 12 years post-initial resection. A female patient, initially diagnosed with mandibular desmoplastic ameloblastoma, revealed masses in both lung fields of the lung on chest radiography, while chest computed tomography revealed more than 10 nodules in both lungs. Histopathological analysis of a lung biopsy specimen revealed a nest-like structure of tumor cells surrounded by highly columnar cells, exhibiting a palisade-like arrangement, and squamous metaplasia.Subsequently, the diagnosis of pulmonary metastatic ameloblastoma was confirmed through immunohistochemical examination. Despite clinical trial treatment with molecular targeted therapy for three years, the lung disease remained clinically stable. This case highlights the need for oral surgeons to recognize that pulmonary metastasis of desmoplastic ameloblastoma can manifest as a late recurrence, extending beyond a decade after initial curative surgery.http://www.sciencedirect.com/science/article/pii/S2405844024165668Desmoplastic ameloblastomaPulmonary metastasisLungMalignant ameloblastoma |
| spellingShingle | Takaaki Kamatani Ryogo Katada Masataka Watanabe Tatsuo Shirota Desmoplastic Ameloblastoma: A case report of rare pulmonary metastasis Heliyon Desmoplastic ameloblastoma Pulmonary metastasis Lung Malignant ameloblastoma |
| title | Desmoplastic Ameloblastoma: A case report of rare pulmonary metastasis |
| title_full | Desmoplastic Ameloblastoma: A case report of rare pulmonary metastasis |
| title_fullStr | Desmoplastic Ameloblastoma: A case report of rare pulmonary metastasis |
| title_full_unstemmed | Desmoplastic Ameloblastoma: A case report of rare pulmonary metastasis |
| title_short | Desmoplastic Ameloblastoma: A case report of rare pulmonary metastasis |
| title_sort | desmoplastic ameloblastoma a case report of rare pulmonary metastasis |
| topic | Desmoplastic ameloblastoma Pulmonary metastasis Lung Malignant ameloblastoma |
| url | http://www.sciencedirect.com/science/article/pii/S2405844024165668 |
| work_keys_str_mv | AT takaakikamatani desmoplasticameloblastomaacasereportofrarepulmonarymetastasis AT ryogokatada desmoplasticameloblastomaacasereportofrarepulmonarymetastasis AT masatakawatanabe desmoplasticameloblastomaacasereportofrarepulmonarymetastasis AT tatsuoshirota desmoplasticameloblastomaacasereportofrarepulmonarymetastasis |