hnRNPU-mediated pathogenic alternative splicing drives gastric cancer progression

hnRNPU-mediated pathogenic alternative splicing drives gastric cancer progression

Abstract Background Alternative splicing (AS) is a process that facilitates the differential inclusion of exonic sequences from precursor messenger RNAs, significantly enhancing the diversity of the transcriptome and proteome. In cancer, pathogenic AS events are closely related to cancer progression...

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Bibliographic Details
Main Authors: Guoguo Jin, Yanming Song, Shaobo Fang, Mingyang Yan, Zhaojie Yang, Yang Shao, Kexin Zhao, Meng Liu, Zhenwei Wang, Zhiping Guo, Zigang Dong
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Gastric cancer
hnRNPU
FTO
Alternative splicing
Online Access:https://doi.org/10.1186/s13046-024-03264-9
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