scRiskCell: A single‐cell framework for quantifying islet risk cells and their adaptive dynamics in type 2 diabetes

scRiskCell: A single‐cell framework for quantifying islet risk cells and their adaptive dynamics in type 2 diabetes

Saved in:

Bibliographic Details
Main Authors:	Xueqin Xie, Changchun Wu, Fuying Dao, Kejun Deng, Dan Yan, Jian Huang, Hao Lyu, Hao Lin
Format:	Article
Language:	English
Published:	Wiley 2025-08-01
Series:	iMeta
Online Access:	https://doi.org/10.1002/imt2.70060
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

BertADP: a fine-tuned protein language model for anti-diabetic peptide prediction
by: Xueqin Xie, et al.
Published: (2025-07-01)

Comprehensive Characterization of Bihormonal Cells and Endocrine Cell Lineages in Mammalian Pancreatic Islets
by: Xin‐Xin Yu, et al.
Published: (2025-08-01)

Islet Transplantation & β-Cell Replacement Therapies for Diabetes
by: Thierry Berney, et al.
Published: (2011-01-01)

Dia-B-Ties: B Cells in the Islet–Immune-Cell Interface in T1D
by: Brandon K. Hilliard, et al.
Published: (2025-02-01)

A message passing framework for precise cell state identification with scClassify2
by: Wenze Ding, et al.
Published: (2025-08-01)

INFLUENCE OF MICROSTRUCTURED COLLAGEN HYDROGEL ON PANCREATIC ISLET CELL CULTURES
by: L. A. Kirsanova, et al.
Published: (2014-05-01)

Impact of Pancreatic Rat Islet Density on Cell Survival during Hypoxia
by: A. Rodriguez-Brotons, et al.
Published: (2016-01-01)

Mitochondrial homeostasis orchestrates the fate of beta‐cells and the outcomes of islet transplantation
by: Baicheng Kuang, et al.
Published: (2025-08-01)

Navigating challenges in human pluripotent stem cell-derived islet therapy for type 1 diabetes
by: Mohammed Usama, et al.
Published: (2025-08-01)

Considerations in biodistribution evaluation of iPSC-derived cell therapy: A pancreatic islet cell case study
by: Miyu Nakayama, et al.
Published: (2025-09-01)

Expression of Transient Receptor Potential Channel Genes and Their Isoforms in Alpha-Cells and Beta-Cells of Human Islets of Langerhans
by: Gabriel M. Matos, et al.
Published: (2022-01-01)

Ryanodine Receptors in Islet Cell Function: Calcium Signaling, Hormone Secretion, and Diabetes
by: Md. Shahidul Islam
Published: (2025-05-01)

Imaging methods to monitor and quantify cell differentiation
by: Kevin Cheah, et al.
Published: (2025-05-01)

Acceleration of Functional Maturation and Differentiation of Neonatal Porcine Islet Cell Monolayers Shortly In Vitro Cocultured with Microencapsulated Sertoli Cells
by: Francesca Mancuso, et al.
Published: (2010-01-01)

scMINER: a mutual information-based framework for clustering and hidden driver inference from single-cell transcriptomics data
by: Qingfei Pan, et al.
Published: (2025-05-01)

Interpretable and integrative analysis of single-cell multiomics with scMKL
by: Samuel D. Kupp, et al.
Published: (2025-08-01)

CellRegMap: a statistical framework for mapping context‐specific regulatory variants using scRNA‐seq
by: Anna S E Cuomo, et al.
Published: (2022-08-01)

Direct and bisulfite-free 5-methylcytosine and 5-hydroxymethylcytosine sequencing at single-cell resolution with scTAPS and scCAPS +
by: Xiufei Chen, et al.
Published: (2025-08-01)

RepliChrom: Interpretable machine learning predicts cancer‐associated enhancer‐promoter interactions using DNA replication timing
by: Fuying Dao, et al.
Published: (2025-08-01)

March5-mediated Trim28 degradation preserves islet β-cell function in mice
by: Yangshan Chen, et al.
Published: (2025-08-01)

IL‐10 producing type 2 innate lymphoid cells prolong islet allograft survival
by: Qingsong Huang, et al.
Published: (2020-10-01)

Quantifying Landscape and Flux from Single-Cell Omics: Unraveling the Physical Mechanisms of Cell Function
by: Ligang Zhu, et al.
Published: (2025-08-01)

Corrigendum to “Wingless-Type MMTV Integration Site Family Member 5a Is a Key Secreted Islet Stellate Cell-Derived Product that Regulates Islet Function”
by: Wei Xu, et al.
Published: (2019-01-01)

scPDA: denoising protein expression in droplet-based single-cell data
by: Ouyang Zhu, et al.
Published: (2025-07-01)

Serum Islet Cell Autoantibodies During Interferon α Treatment in Patients With HCV-Genotype 4 Chronic Hepatitis
by: Gamal Badra, et al.
Published: (2006-01-01)

Ophiopogonin D improves pancreatic islet cell dedifferentiation to treat diabetes by regulating the GRP78/ROS/PDX1 signaling pathway
by: Haoxiang Sun, et al.
Published: (2025-04-01)

RISK FACTORS FOR RENAL CELL CARCINOMA
by: D. G. Zaridze, et al.
Published: (2018-11-01)

Risk factors for cell culture contamination
by: Egorushkina E.I., Neminushchaya L.A., Skotnikova T.A., Startsev D. A., Grin S.A., et al.
Published: (2025-06-01)

UCP2 inhibition eliminates pancreatic β cell autoinflammation in T2DM with islet-mitochondrial sequential targeting nanomedicines
by: Zerun Liu, et al.
Published: (2025-07-01)

Functional architecture of pancreatic islets identifies a population of first responder cells that drive the first-phase calcium response.
by: Vira Kravets, et al.
Published: (2022-09-01)

scClassify: sample size estimation and multiscale classification of cells using single and multiple reference
by: Yingxin Lin, et al.
Published: (2020-06-01)

scQTLtools: An R/Bioconductor Package for Comprehensive Identification and Visualization of Single-Cell eQTLs
by: Xiaofeng Wu, et al.
Published: (2025-06-01)

IT-scC&T-seq streamlines scalable, parallel profiling of protein–DNA interactions in single cells
by: Jingchun Ma, et al.
Published: (2025-07-01)

Quantifying Temporal Dynamics in Global Cyber Threats: A GPT-Driven Framework for Risk Forecasting and Strategic Intelligence
by: Fahim Sufi, et al.
Published: (2025-05-01)

Integrative single-cell multi-omics profiling of human pancreatic islets identifies T1D-associated genes and regulatory signals
by: Ricardo D'Oliveira Albanus, et al.
Published: (2025-08-01)

Major cell types in the coronary thrombosis of acute myocardial infarction patients revealed by scRNA‐seq
by: Zhiyao Wei, et al.
Published: (2025-01-01)

Glucocorticoid signaling in pancreatic islets modulates gene regulatory programs and genetic risk of type 2 diabetes.
by: Anthony Aylward, et al.
Published: (2021-05-01)

The challenge of accurately quantifying future megadrought risk in the American Southwest
by: Sloan Coats, et al.
Published: (2016-09-01)

Competing risk of death in patients with low, intermediate and high risk of recurrence after radical surgery for clear cell renal cell carcinoma
by: Anna Brännbäck, et al.
Published: (2025-07-01)

NeXtMD: a new generation of machine learning and deep learning stacked hybrid framework for accurate identification of anti-inflammatory peptides
by: Chengzhi Xie, et al.
Published: (2025-07-01)