Research progress of drug resistance mechanism of temozolomide in the treatment of glioblastoma

Glioblastoma, the most malignant primary brain tumor among gliomas, is characterized by a low cure rate, high recurrence rate, and invasive growth. Without chemotherapy, the median survival of patients is only 12.1 months. The standard treatment for glioblastoma primarily involves surgical resection...

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Bibliographic Details
Main Authors: Hao Wu, Wenwen Gao, Peng Chen, Yao Wei, Haikang Zhao, Fenglu Wang
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S240584402416015X
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