Poly hydroxyalkanoates (PHA): Role in bone scaffolds
Polyhydroxyalkanoates (PHA) are prokaryotic macromolecules accumulated within the cytoplasm as granules. Due to their suitable mechanical properties, biocompatibility, degradation time, ability to be blended, surface modified, and form copolymers, it is widely used in medical devices and as scaffold...
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| Format: | Article |
| Language: | English |
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Elsevier
2020-01-01
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| Series: | Journal of Oral Biology and Craniofacial Research |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2212426819302556 |
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| author | Ruby Dwivedi Rahul Pandey Sumit Kumar Divya Mehrotra |
| author_facet | Ruby Dwivedi Rahul Pandey Sumit Kumar Divya Mehrotra |
| author_sort | Ruby Dwivedi |
| collection | DOAJ |
| description | Polyhydroxyalkanoates (PHA) are prokaryotic macromolecules accumulated within the cytoplasm as granules. Due to their suitable mechanical properties, biocompatibility, degradation time, ability to be blended, surface modified, and form copolymers, it is widely used in medical devices and as scaffolds in bone tissue engineering. This review describes in brief the production and extraction sources, physico-chemical characteristic, mechanical properties, degradation rate and applications of various PHAs and its copolymers with special emphasis to its role as scaffolds in bone tissue engineering. |
| format | Article |
| id | doaj-art-d2d506e1904b4ab78b1527807cbba9c3 |
| institution | Kabale University |
| issn | 2212-4268 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Oral Biology and Craniofacial Research |
| spelling | doaj-art-d2d506e1904b4ab78b1527807cbba9c32024-11-23T06:27:53ZengElsevierJournal of Oral Biology and Craniofacial Research2212-42682020-01-01101389392Poly hydroxyalkanoates (PHA): Role in bone scaffoldsRuby Dwivedi0Rahul Pandey1Sumit Kumar2Divya Mehrotra3Department of Oral and Maxillofacial Surgery, Faculty of Dental Sciences, KGMU, Lucknow, UP, IndiaDHR-MRU, Faculty of Dental Sciences, KGMU, Lucknow, UP, IndiaDHR-MRU, Faculty of Dental Sciences, KGMU, Lucknow, UP, IndiaDHR-MRU, Faculty of Dental Sciences, KGMU, Lucknow, UP, India; Corresponding author. Dept of Oral and Maxillofacial Surgery, Faculty of Dental Sciences, KG medical University, Chowk, Lucknow, 226003, UP, India.Polyhydroxyalkanoates (PHA) are prokaryotic macromolecules accumulated within the cytoplasm as granules. Due to their suitable mechanical properties, biocompatibility, degradation time, ability to be blended, surface modified, and form copolymers, it is widely used in medical devices and as scaffolds in bone tissue engineering. This review describes in brief the production and extraction sources, physico-chemical characteristic, mechanical properties, degradation rate and applications of various PHAs and its copolymers with special emphasis to its role as scaffolds in bone tissue engineering.http://www.sciencedirect.com/science/article/pii/S2212426819302556PolyhydroxyalkanoatesPolyhydroxybutyrateScaffoldsBone tissue engineering |
| spellingShingle | Ruby Dwivedi Rahul Pandey Sumit Kumar Divya Mehrotra Poly hydroxyalkanoates (PHA): Role in bone scaffolds Journal of Oral Biology and Craniofacial Research Polyhydroxyalkanoates Polyhydroxybutyrate Scaffolds Bone tissue engineering |
| title | Poly hydroxyalkanoates (PHA): Role in bone scaffolds |
| title_full | Poly hydroxyalkanoates (PHA): Role in bone scaffolds |
| title_fullStr | Poly hydroxyalkanoates (PHA): Role in bone scaffolds |
| title_full_unstemmed | Poly hydroxyalkanoates (PHA): Role in bone scaffolds |
| title_short | Poly hydroxyalkanoates (PHA): Role in bone scaffolds |
| title_sort | poly hydroxyalkanoates pha role in bone scaffolds |
| topic | Polyhydroxyalkanoates Polyhydroxybutyrate Scaffolds Bone tissue engineering |
| url | http://www.sciencedirect.com/science/article/pii/S2212426819302556 |
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