Prevalence and treatment patterns of erectile dysfunction and hypogonadism in men with spina bifida: a retrospective study
ObjectivesTo characterize the estimated prevalence and treatment patterns of erectile dysfunction and hypogonadism in men with spina bifida through a large claims database.MethodsThis retrospective claims study used the MarketScan® databases from 2008 to 2017 to compare prevalence estimates for erec...
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Frontiers Media S.A.
2025-03-01
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| Series: | Frontiers in Urology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fruro.2025.1500839/full |
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| author | Nyemkuna Fortingo Manpreet Sandhu Garrick Greear Tung-Chin Hsieh Joshua Horns Rupam Das Jim Hotaling Yahir Santiago-Lastra |
| author_facet | Nyemkuna Fortingo Manpreet Sandhu Garrick Greear Tung-Chin Hsieh Joshua Horns Rupam Das Jim Hotaling Yahir Santiago-Lastra |
| author_sort | Nyemkuna Fortingo |
| collection | DOAJ |
| description | ObjectivesTo characterize the estimated prevalence and treatment patterns of erectile dysfunction and hypogonadism in men with spina bifida through a large claims database.MethodsThis retrospective claims study used the MarketScan® databases from 2008 to 2017 to compare prevalence estimates for erectile dysfunction and hypogonadism in men with spina bifida to those in men without spina bifida and to describe treatment patterns in this cohort.ResultsThe estimated prevalence of erectile dysfunction and hypogonadism in men with spina bifida was 7.83% and 7.71%, respectively. Men with spina bifida exhibit high rates of smoking and metabolic comorbidities but are diagnosed less frequently with erectile dysfunction when controlling for age and metabolic comorbidities than men without spina bifida. Most men with spina bifida and erectile dysfunction (66.6%) or hypogonadism (77.4%) do not receive treatment. However, a diagnosis of spina bifida did not appear to affect the likelihood of treatment for either condition on multivariate analysis.ConclusionsMen with spina bifida are known to be at high risk for erectile dysfunction but may be diagnosed or treated less frequently than age and disease-matched men without spina bifida. Hypogonadism is diagnosed more frequently in men with spina bifida, which is a new finding that warrants further investigation. Most men with SB and either ED or HG do not receive treatment. The results suggest there is potential for improving care delivery for sexual health issues in men with spina bifida. |
| format | Article |
| id | doaj-art-d2d1c0d3c0a3491c94e38e75b35f6221 |
| institution | DOAJ |
| issn | 2673-9828 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Urology |
| spelling | doaj-art-d2d1c0d3c0a3491c94e38e75b35f62212025-08-20T02:52:45ZengFrontiers Media S.A.Frontiers in Urology2673-98282025-03-01510.3389/fruro.2025.15008391500839Prevalence and treatment patterns of erectile dysfunction and hypogonadism in men with spina bifida: a retrospective studyNyemkuna Fortingo0Manpreet Sandhu1Garrick Greear2Tung-Chin Hsieh3Joshua Horns4Rupam Das5Jim Hotaling6Yahir Santiago-Lastra7Division of Urology, Virginia Commonwealth University Health System, Richmond, VA, United StatesSchool of Medicine, University of California, San Diego, San Diego, CA, United StatesThe Urology Center of Colorado, Denver, CO, United StatesDepartment of Urology, University of California, San Diego, La Jolla, CA, United StatesDivision of Urology, University of Utah, Salt Lake City, UT, United StatesDivision of Urology, University of Utah, Salt Lake City, UT, United StatesDivision of Urology, University of Utah, Salt Lake City, UT, United StatesDepartment of Urology, University of California, San Diego, La Jolla, CA, United StatesObjectivesTo characterize the estimated prevalence and treatment patterns of erectile dysfunction and hypogonadism in men with spina bifida through a large claims database.MethodsThis retrospective claims study used the MarketScan® databases from 2008 to 2017 to compare prevalence estimates for erectile dysfunction and hypogonadism in men with spina bifida to those in men without spina bifida and to describe treatment patterns in this cohort.ResultsThe estimated prevalence of erectile dysfunction and hypogonadism in men with spina bifida was 7.83% and 7.71%, respectively. Men with spina bifida exhibit high rates of smoking and metabolic comorbidities but are diagnosed less frequently with erectile dysfunction when controlling for age and metabolic comorbidities than men without spina bifida. Most men with spina bifida and erectile dysfunction (66.6%) or hypogonadism (77.4%) do not receive treatment. However, a diagnosis of spina bifida did not appear to affect the likelihood of treatment for either condition on multivariate analysis.ConclusionsMen with spina bifida are known to be at high risk for erectile dysfunction but may be diagnosed or treated less frequently than age and disease-matched men without spina bifida. Hypogonadism is diagnosed more frequently in men with spina bifida, which is a new finding that warrants further investigation. Most men with SB and either ED or HG do not receive treatment. The results suggest there is potential for improving care delivery for sexual health issues in men with spina bifida.https://www.frontiersin.org/articles/10.3389/fruro.2025.1500839/fullspina bifida (SB)erectile dysfunctionhypogonadismhealth disparitiesmyelomeningocelesexual health |
| spellingShingle | Nyemkuna Fortingo Manpreet Sandhu Garrick Greear Tung-Chin Hsieh Joshua Horns Rupam Das Jim Hotaling Yahir Santiago-Lastra Prevalence and treatment patterns of erectile dysfunction and hypogonadism in men with spina bifida: a retrospective study Frontiers in Urology spina bifida (SB) erectile dysfunction hypogonadism health disparities myelomeningocele sexual health |
| title | Prevalence and treatment patterns of erectile dysfunction and hypogonadism in men with spina bifida: a retrospective study |
| title_full | Prevalence and treatment patterns of erectile dysfunction and hypogonadism in men with spina bifida: a retrospective study |
| title_fullStr | Prevalence and treatment patterns of erectile dysfunction and hypogonadism in men with spina bifida: a retrospective study |
| title_full_unstemmed | Prevalence and treatment patterns of erectile dysfunction and hypogonadism in men with spina bifida: a retrospective study |
| title_short | Prevalence and treatment patterns of erectile dysfunction and hypogonadism in men with spina bifida: a retrospective study |
| title_sort | prevalence and treatment patterns of erectile dysfunction and hypogonadism in men with spina bifida a retrospective study |
| topic | spina bifida (SB) erectile dysfunction hypogonadism health disparities myelomeningocele sexual health |
| url | https://www.frontiersin.org/articles/10.3389/fruro.2025.1500839/full |
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