Global effects of DNA replication and DNA replication origin activity on eukaryotic gene expression

Global effects of DNA replication and DNA replication origin activity on eukaryotic gene expression

Abstract This report provides a global view of how gene expression is affected by DNA replication. We analyzed synchronized cultures of Saccharomyces cerevisiae under conditions that prevent DNA replication initiation without delaying cell cycle progression. We use a higher‐order singular value deco...

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Bibliographic Details
Main Authors: Larsson Omberg, Joel R Meyerson, Kayta Kobayashi, Lucy S Drury, John F X Diffley, Orly Alter
Format: Article
Language:English
Published: Springer Nature 2009-10-01
Series:Molecular Systems Biology
Subjects:
a higher‐order singular value decomposition (HOSVD)
cell cycle
DNA replication origin licensing and firing
DNA microarrays
mRNA expression
Online Access:https://doi.org/10.1038/msb.2009.70
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https://doi.org/10.1038/msb.2009.70

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