CD91-mediated reprogramming of DCs by immunogenic heat shock proteins requires the kinases AXL and Fgr
Abstract Immune responses to tumors, comprising adaptive T cells and innate NK cells, arise very early in tumorigeneses and prior to detection of palpable tumors or before tissue pathology is evident. Yet, how nascent tumors evoke dendritic cell maturation and the resulting cytokine responses that a...
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| Main Authors: | James Trey F. Harkness, Devanshi A. Nayak, Abigail L. Sedlacek, Richard Cattley, William F. Hawse, Simon C. Watkins, Robert J. Binder |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-12-01
|
| Series: | Cell Communication and Signaling |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12964-024-01901-6 |
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