Regulation of ADAM10 activity through microdomain-dependent intracellular calcium changes
Abstract A disintegrin and metalloproteinases (ADAMs) are transmembrane proteases that cleave other proteins close to the surface in a process called shedding. The prominent member ADAM10 has been linked to several pathologies such as Alzheimer’s disease, bacterial infection, cancer development and...
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| Main Authors: | Federico Guillermo Gharzia, Ahmad Aljohmani, Andreas Beck, Stephan E. Philipp, Daniela Yildiz |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-11-01
|
| Series: | Cell Communication and Signaling |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12964-024-01891-5 |
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