The mediating role of physical activity, morning wake-up time, and sleep-inducing medication use in the relationship between age and depression: a path analysis of a large kurdish cohort study in Iran

Abstract Background Depression is a common and debilitating psychiatric disorder worldwide. Recognizing the relationships between depression-related factors can play a significant role in depression management. However, no study has yet used path analysis to examine the mediating role of physical ac...

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Main Authors: Fahimeh Alsadat Hosseini, Samaneh Bagherian, Cristina Cañete-Massé, Mehdi Moradinazar, Farid Najafi
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Public Health
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Online Access:https://doi.org/10.1186/s12889-024-21262-6
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author Fahimeh Alsadat Hosseini
Samaneh Bagherian
Cristina Cañete-Massé
Mehdi Moradinazar
Farid Najafi
author_facet Fahimeh Alsadat Hosseini
Samaneh Bagherian
Cristina Cañete-Massé
Mehdi Moradinazar
Farid Najafi
author_sort Fahimeh Alsadat Hosseini
collection DOAJ
description Abstract Background Depression is a common and debilitating psychiatric disorder worldwide. Recognizing the relationships between depression-related factors can play a significant role in depression management. However, no study has yet used path analysis to examine the mediating role of physical activity, morning wake-up time, and sleep-inducing medication in the relationship between age and depression. Methods This path analysis study utilized data from the baseline phase of the Ravansar non-communicable disease cohort study. This study was conducted on people aged 35 to 65 years using sociodemographic, clinical, and the PERSIAN cohort’s standard physical activity questionnaires. These analyses were done using SPSS (version 22) and MPLUS (version 8.3). Path analysis was applied to evaluate the direct, indirect, and total effects of age on depression. Results The results indicated that increasing age was associated with an increase in depression through a decrease in physical activity and an increase in sleep-inducing medication use. In addition, an increase in age was significantly related to a reduced incidence of depression via an earlier morning wake-up time. Discussion We found evidence for a mediational effect of age on depression, as the biopsychosocial model of mental illness implies. The findings of this study can add to the existing body of knowledge on depression management and help clarify the mechanisms of the effect of age on depression.
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spelling doaj-art-d254cd0bc9b54849aac0a4630f9b6c2f2025-01-12T12:42:32ZengBMCBMC Public Health1471-24582025-01-0125111010.1186/s12889-024-21262-6The mediating role of physical activity, morning wake-up time, and sleep-inducing medication use in the relationship between age and depression: a path analysis of a large kurdish cohort study in IranFahimeh Alsadat Hosseini0Samaneh Bagherian1Cristina Cañete-Massé2Mehdi Moradinazar3Farid Najafi4Community Based Psychiatric Care Research Center, School of Nursing and Midwifery, Shiraz University of Medical SciencesDepartment of Operating Room, School of Paramedical Sciences, Geriatric Health Research Center, Birjand University of Medical SciencesDepartment of Social Psychology and Quantitative Psychology, Faculty of Psychology, Universitat de BarcelonaResearch Center for Environmental Determinants of Health (RCEDH), Health Institute, Kermanshah University of Medical SciencesResearch Center for Environmental Determinants of Health (RCEDH), Health Institute, Kermanshah University of Medical SciencesAbstract Background Depression is a common and debilitating psychiatric disorder worldwide. Recognizing the relationships between depression-related factors can play a significant role in depression management. However, no study has yet used path analysis to examine the mediating role of physical activity, morning wake-up time, and sleep-inducing medication in the relationship between age and depression. Methods This path analysis study utilized data from the baseline phase of the Ravansar non-communicable disease cohort study. This study was conducted on people aged 35 to 65 years using sociodemographic, clinical, and the PERSIAN cohort’s standard physical activity questionnaires. These analyses were done using SPSS (version 22) and MPLUS (version 8.3). Path analysis was applied to evaluate the direct, indirect, and total effects of age on depression. Results The results indicated that increasing age was associated with an increase in depression through a decrease in physical activity and an increase in sleep-inducing medication use. In addition, an increase in age was significantly related to a reduced incidence of depression via an earlier morning wake-up time. Discussion We found evidence for a mediational effect of age on depression, as the biopsychosocial model of mental illness implies. The findings of this study can add to the existing body of knowledge on depression management and help clarify the mechanisms of the effect of age on depression.https://doi.org/10.1186/s12889-024-21262-6Physical activitySleep aidsAgeDepressionPERSIAN
spellingShingle Fahimeh Alsadat Hosseini
Samaneh Bagherian
Cristina Cañete-Massé
Mehdi Moradinazar
Farid Najafi
The mediating role of physical activity, morning wake-up time, and sleep-inducing medication use in the relationship between age and depression: a path analysis of a large kurdish cohort study in Iran
BMC Public Health
Physical activity
Sleep aids
Age
Depression
PERSIAN
title The mediating role of physical activity, morning wake-up time, and sleep-inducing medication use in the relationship between age and depression: a path analysis of a large kurdish cohort study in Iran
title_full The mediating role of physical activity, morning wake-up time, and sleep-inducing medication use in the relationship between age and depression: a path analysis of a large kurdish cohort study in Iran
title_fullStr The mediating role of physical activity, morning wake-up time, and sleep-inducing medication use in the relationship between age and depression: a path analysis of a large kurdish cohort study in Iran
title_full_unstemmed The mediating role of physical activity, morning wake-up time, and sleep-inducing medication use in the relationship between age and depression: a path analysis of a large kurdish cohort study in Iran
title_short The mediating role of physical activity, morning wake-up time, and sleep-inducing medication use in the relationship between age and depression: a path analysis of a large kurdish cohort study in Iran
title_sort mediating role of physical activity morning wake up time and sleep inducing medication use in the relationship between age and depression a path analysis of a large kurdish cohort study in iran
topic Physical activity
Sleep aids
Age
Depression
PERSIAN
url https://doi.org/10.1186/s12889-024-21262-6
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