Weighing options: empiric antibiotic use and stewardship opportunities in critically ill patients with community-acquired pneumonia

In this retrospective study, critically ill patients with community-acquired pneumonia frequently received empiric anti-methicillin-resistant Staphylococcus aureus (MRSA) and antipseudomonal antibiotics despite having few or no guidelines-endorsed risk factors. De-escalation of anti-MRSA therapy was...

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Main Authors: Nalea Trujillo, Calvin Diep, David Ha, Ariadna Garcia, Marisa Holubar
Format: Article
Language:English
Published: Cambridge University Press 2025-01-01
Series:Antimicrobial Stewardship & Healthcare Epidemiology
Online Access:https://www.cambridge.org/core/product/identifier/S2732494X2510082X/type/journal_article
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author Nalea Trujillo
Calvin Diep
David Ha
Ariadna Garcia
Marisa Holubar
author_facet Nalea Trujillo
Calvin Diep
David Ha
Ariadna Garcia
Marisa Holubar
author_sort Nalea Trujillo
collection DOAJ
description In this retrospective study, critically ill patients with community-acquired pneumonia frequently received empiric anti-methicillin-resistant Staphylococcus aureus (MRSA) and antipseudomonal antibiotics despite having few or no guidelines-endorsed risk factors. De-escalation of anti-MRSA therapy was quicker, likely aided by MRSA polymerase chain reaction assays.
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institution Kabale University
issn 2732-494X
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publishDate 2025-01-01
publisher Cambridge University Press
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series Antimicrobial Stewardship & Healthcare Epidemiology
spelling doaj-art-d22621a788ed44f8b17b2f4b0efa2dd82025-08-20T04:00:32ZengCambridge University PressAntimicrobial Stewardship & Healthcare Epidemiology2732-494X2025-01-01510.1017/ash.2025.10082Weighing options: empiric antibiotic use and stewardship opportunities in critically ill patients with community-acquired pneumoniaNalea Trujillo0https://orcid.org/0009-0008-8624-5530Calvin Diep1https://orcid.org/0000-0002-6238-2011David Ha2Ariadna Garcia3https://orcid.org/0000-0001-6740-7081Marisa Holubar4https://orcid.org/0000-0002-7585-1809Department of Pharmacy, Stanford Health Care, Stanford, CA, USADepartment of Pharmacy, Stanford Health Care, Stanford, CA, USADivision of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, CA, USA Department of Quality, Stanford Health Care, Stanford, CA, USAStanford University School of Medicine, Quantitative Sciences Unit, Stanford, CA, USADivision of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, CA, USAIn this retrospective study, critically ill patients with community-acquired pneumonia frequently received empiric anti-methicillin-resistant Staphylococcus aureus (MRSA) and antipseudomonal antibiotics despite having few or no guidelines-endorsed risk factors. De-escalation of anti-MRSA therapy was quicker, likely aided by MRSA polymerase chain reaction assays.https://www.cambridge.org/core/product/identifier/S2732494X2510082X/type/journal_article
spellingShingle Nalea Trujillo
Calvin Diep
David Ha
Ariadna Garcia
Marisa Holubar
Weighing options: empiric antibiotic use and stewardship opportunities in critically ill patients with community-acquired pneumonia
Antimicrobial Stewardship & Healthcare Epidemiology
title Weighing options: empiric antibiotic use and stewardship opportunities in critically ill patients with community-acquired pneumonia
title_full Weighing options: empiric antibiotic use and stewardship opportunities in critically ill patients with community-acquired pneumonia
title_fullStr Weighing options: empiric antibiotic use and stewardship opportunities in critically ill patients with community-acquired pneumonia
title_full_unstemmed Weighing options: empiric antibiotic use and stewardship opportunities in critically ill patients with community-acquired pneumonia
title_short Weighing options: empiric antibiotic use and stewardship opportunities in critically ill patients with community-acquired pneumonia
title_sort weighing options empiric antibiotic use and stewardship opportunities in critically ill patients with community acquired pneumonia
url https://www.cambridge.org/core/product/identifier/S2732494X2510082X/type/journal_article
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