A new pipeline SPICE identifies novel JUN-IKZF1 composite elements

A new pipeline SPICE identifies novel JUN-IKZF1 composite elements

Transcription factor partners can cooperatively bind to DNA composite elements to augment gene transcription. Here, we report a novel protein-DNA binding screening pipeline, termed Spacing Preference Identification of Composite Elements (SPICE), that can systematically predict protein binding partne...

Full description

Saved in:
Bibliographic Details
Main Authors: Peng Li, Sree Pulugulla, Sonali Das, Jangsuk Oh, Rosanne Spolski, Jian-Xin Lin, Warren J Leonard
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-01-01
Series:eLife
Subjects:
Protein-DNA
IKZF1
SPICE
JUN
AP1
IL-21
Online Access:https://elifesciences.org/articles/88833
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items