Protective effects of miR-24-2-5p in early stages of breast cancer bone metastasis

Protective effects of miR-24-2-5p in early stages of breast cancer bone metastasis

Abstract Background Bone is the most frequent site of metastasis for breast cancer (BC). Metastatic BC cells interact with bone cells, including osteoclasts and osteoblasts, creating a cancer niche where they seed and proliferate. MicroRNAs (miRNAs) are regulators of breast-to-bone metastasis progre...

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Main Authors: Margherita Puppo, Martine Croset, Davide Ceresa, Manoj Kumar Valluru, Victor Gabriel Canuas Landero, Monserrat Hernandez Guadarrama, Michele Iuliani, Francesco Pantano, Penelope Dawn Ottewell, Philippe Clézardin
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Breast Cancer Research
Subjects:
Breast cancer
Bone metastasis
Early-stage
Osteoclasts
miR-24
Small extracellular vesicles
Online Access:https://doi.org/10.1186/s13058-024-01934-2
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