Postsynaptic spiking determines anti-Hebbian LTD in visual cortex basket cells

Postsynaptic spiking determines anti-Hebbian LTD in visual cortex basket cells

Long-term plasticity at pyramidal cell to basket cell (PC → BC) synapses is important for the functioning of cortical microcircuits. It is well known that at neocortical PC → PC synapses, dendritic calcium (Ca2+) dynamics signal coincident pre-and postsynaptic spiking which in turn triggers long-ter...

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Bibliographic Details
Main Authors: Christina Y. C. Chou, Wouter J. Droogers, Txomin Lalanne, Eric Fineberg, Tal Klimenko, Hannah Owens, P. Jesper Sjöström
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
inhibitory interneurons
plasticity
synapse
spike-timing dependent plasticity
visual cortex
action potential backpropagation
Online Access:https://www.frontiersin.org/articles/10.3389/fnsyn.2025.1548563/full
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