Demographics, Clinical, and Microbiological Characteristics of Men with Urethritis in Cyprus
Objective: Urethritis is a common sexually transmitted disease (STD) in developing countries; however, up to 40% of cases have no determined etiology. The characteristics of STDs vary geographically. This study aimed to define the demographic, clinical, and microbiological features of men with ureth...
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Galenos Publishing House
2024-01-01
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| Series: | Gazi Medical Journal |
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| Online Access: | https://gazimedj.com/articles/demographics-clinical-and-microbiological-characteristics-of-men-with-urethritis-in-cyprus/doi/gmj.galenos.2023.3712 |
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| _version_ | 1841525491944652800 |
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| author | Hakan Evren Emine Ünal Evren Çetin Volkan Öztekin |
| author_facet | Hakan Evren Emine Ünal Evren Çetin Volkan Öztekin |
| author_sort | Hakan Evren |
| collection | DOAJ |
| description | Objective: Urethritis is a common sexually transmitted disease (STD) in developing countries; however, up to 40% of cases have no determined etiology. The characteristics of STDs vary geographically. This study aimed to define the demographic, clinical, and microbiological features of men with urethritis in Cyprus, where current data in the literature are lacking.
Methods: We included 138 patients who sought care at a university hospital in Cyprus from 2017 to 2021 and had symptoms suggestive of urethritis or a history of a recent sexual partner with STD. Urethral swab samples of the patients were tested for seven pathogens (Trichomonas vaginalis, Neisseria gonorrhoeae (N. gonorrhoeae), Chlamydia trachomatis (C. trachomatis), Ureaplasma urealyticum (U. urealyticum), Ureaplasma parvum (U. parvum), Mycoplasma genitalium (M. genitalium), Mycoplasma hominis (M. hominis) by multiplex polymerase chain reaction assay. In addition, demographic, clinical, and microbiological data were obtained from the hospital program and analyzed.
Results: Pathogens were detected in 59.4% of the cases: U. urealyticum in 26.8%, C. trachomatis in 13%, N. gonorrhoeae in 9.4%, U. parvum in 10.1%, M. genitalium in 10.1%, and M. hominis in 10.9%, with multiple microorganisms detected in 18.1%. Overall, 80.4% of the cases were symptomatic at presentation, and pathogen detection was associated with a history of STD, multiple sexual partners, and unprotected sexual intercourse.
Conclusions: Urethritis is a common and heterogeneous clinical condition. U. urealyticum dominates male urethritis in Cyprus, yet many individuals have no detectable microorganisms. Future studies should focus on developing more comprehensive quantitative molecular diagnostic methods with determined cycle threshold values to shed light on the pathogenic roles of commensal microorganisms. |
| format | Article |
| id | doaj-art-d18ca72d63f044b38c377f991a6a783f |
| institution | Kabale University |
| issn | 2147-2092 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Gazi Medical Journal |
| spelling | doaj-art-d18ca72d63f044b38c377f991a6a783f2025-01-17T11:34:22ZengGalenos Publishing HouseGazi Medical Journal2147-20922024-01-01351384110.12996/gmj.galenos.2023.3712Demographics, Clinical, and Microbiological Characteristics of Men with Urethritis in CyprusHakan Evren0https://orcid.org/0000-0001-8247-8144Emine Ünal Evren1https://orcid.org/0000-0001-9455-0473Çetin Volkan Öztekin2https://orcid.org/0000-0003-2082-2135University of Kyrenia School of Medicine, Department of Infectious Diseases and Clinical Microbiology, Kyrenia, North CyprusUniversity of Kyrenia School of Medicine, Department of Infectious Diseases and Clinical Microbiology, Kyrenia, North CyprusUniversity of Kyrenia School of Medicine, Department of Urology, Kyrenia, North CyprusObjective: Urethritis is a common sexually transmitted disease (STD) in developing countries; however, up to 40% of cases have no determined etiology. The characteristics of STDs vary geographically. This study aimed to define the demographic, clinical, and microbiological features of men with urethritis in Cyprus, where current data in the literature are lacking. Methods: We included 138 patients who sought care at a university hospital in Cyprus from 2017 to 2021 and had symptoms suggestive of urethritis or a history of a recent sexual partner with STD. Urethral swab samples of the patients were tested for seven pathogens (Trichomonas vaginalis, Neisseria gonorrhoeae (N. gonorrhoeae), Chlamydia trachomatis (C. trachomatis), Ureaplasma urealyticum (U. urealyticum), Ureaplasma parvum (U. parvum), Mycoplasma genitalium (M. genitalium), Mycoplasma hominis (M. hominis) by multiplex polymerase chain reaction assay. In addition, demographic, clinical, and microbiological data were obtained from the hospital program and analyzed. Results: Pathogens were detected in 59.4% of the cases: U. urealyticum in 26.8%, C. trachomatis in 13%, N. gonorrhoeae in 9.4%, U. parvum in 10.1%, M. genitalium in 10.1%, and M. hominis in 10.9%, with multiple microorganisms detected in 18.1%. Overall, 80.4% of the cases were symptomatic at presentation, and pathogen detection was associated with a history of STD, multiple sexual partners, and unprotected sexual intercourse. Conclusions: Urethritis is a common and heterogeneous clinical condition. U. urealyticum dominates male urethritis in Cyprus, yet many individuals have no detectable microorganisms. Future studies should focus on developing more comprehensive quantitative molecular diagnostic methods with determined cycle threshold values to shed light on the pathogenic roles of commensal microorganisms.https://gazimedj.com/articles/demographics-clinical-and-microbiological-characteristics-of-men-with-urethritis-in-cyprus/doi/gmj.galenos.2023.3712urethritisneisseria gonorrhoeaechlamydia trachomatisureaplasma urealyticumsexually transmitted diseasesureaplasma parvum |
| spellingShingle | Hakan Evren Emine Ünal Evren Çetin Volkan Öztekin Demographics, Clinical, and Microbiological Characteristics of Men with Urethritis in Cyprus Gazi Medical Journal urethritis neisseria gonorrhoeae chlamydia trachomatis ureaplasma urealyticum sexually transmitted diseases ureaplasma parvum |
| title | Demographics, Clinical, and Microbiological Characteristics of Men with Urethritis in Cyprus |
| title_full | Demographics, Clinical, and Microbiological Characteristics of Men with Urethritis in Cyprus |
| title_fullStr | Demographics, Clinical, and Microbiological Characteristics of Men with Urethritis in Cyprus |
| title_full_unstemmed | Demographics, Clinical, and Microbiological Characteristics of Men with Urethritis in Cyprus |
| title_short | Demographics, Clinical, and Microbiological Characteristics of Men with Urethritis in Cyprus |
| title_sort | demographics clinical and microbiological characteristics of men with urethritis in cyprus |
| topic | urethritis neisseria gonorrhoeae chlamydia trachomatis ureaplasma urealyticum sexually transmitted diseases ureaplasma parvum |
| url | https://gazimedj.com/articles/demographics-clinical-and-microbiological-characteristics-of-men-with-urethritis-in-cyprus/doi/gmj.galenos.2023.3712 |
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