Establishment of a New Hyperglycemic Obesity Cardiac Dysfunction Mouse Model with Triacsin C

Establishment of a New Hyperglycemic Obesity Cardiac Dysfunction Mouse Model with Triacsin C

Objective This study aims to establish a novel hyperglycemic obesity mouse model by utilizing Triacsin C, an inhibitor of acyl-CoA synthetase long-chain family member 1 (ACSL1), combined with a high-fat diet, to simulate the changes in adipose tissue and cardiac function observed in patients with ob...

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Bibliographic Details
Main Authors: ZHAO Xiaona, WANG Peng, YE Maoqing, QU Xinkai
Format: Article
Language:zho
Published: Editorial Office of Laboratory Animal and Comparative Medicine 2024-12-01
Series:Shiyan dongwu yu bijiao yixue
Subjects:
animal model
acyl-coa synthetase long-chain family member 1
brown adipose tissue
cardiac dysfunction
mice
Online Access:https://www.slarc.org.cn/dwyx/CN/10.12300/j.issn.1674-5817.2024.078
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