Significantly improving the solubility and anti-inflammatory activity of fenofibric acid with native and methyl-substituted beta-cyclodextrins via complexation

Significantly improving the solubility and anti-inflammatory activity of fenofibric acid with native and methyl-substituted beta-cyclodextrins via complexation

Abstract The solubility of commonly used anti-inflammatory drugs has become a significant concern in contemporary medicine. Furthermore, inflammatory arthritis stands out as the most prevalent chronic inflammatory disease globally. The disease’s pathology is characterized by heightened inflammation...

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Main Authors: Rajaram Rajamohan, Perumal Muthuraja, Kuppusamy Murugavel, Murali Krishnan Mani, D. S. Prabakaran, Jeong Hyun Seo, Tabarak Malik, Yong Rok Lee
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Fenofibric acid
Beta-cyclodextrins
Complexation
ROESY analysis
Anti-inflammation
MTT assay
Online Access:https://doi.org/10.1038/s41598-024-84745-x
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https://doi.org/10.1038/s41598-024-84745-x

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