Large-bodied gastric spirurids (Nematoda, Spirurida) predict structure in the downstream gastrointestinal helminth community of wild spiny mice (Acomys dimidiatus)

The dominant helminths infecting spiny mice (Acomys dimidiatus) in the montane wadis of the Sinai Peninsula of Egypt are spirurid nematodes, notably Protospirura muricola and Mastophorus muris. Both are relatively large robust stomach worms that accumulate in hosts resulting in high worm burdens. To...

Full description

Saved in:
Bibliographic Details
Main Authors: Jerzy M. Behnke, Joseph A. Jackson, Francis Gilbert, Eman M. E. Mohallal, Anna Bajer
Format: Article
Language:English
Published: Cambridge University Press 2024-07-01
Series:Parasitology
Subjects:
Online Access:https://www.cambridge.org/core/product/identifier/S0031182024000891/type/journal_article
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1846166568368603136
author Jerzy M. Behnke
Joseph A. Jackson
Francis Gilbert
Eman M. E. Mohallal
Anna Bajer
author_facet Jerzy M. Behnke
Joseph A. Jackson
Francis Gilbert
Eman M. E. Mohallal
Anna Bajer
author_sort Jerzy M. Behnke
collection DOAJ
description The dominant helminths infecting spiny mice (Acomys dimidiatus) in the montane wadis of the Sinai Peninsula of Egypt are spirurid nematodes, notably Protospirura muricola and Mastophorus muris. Both are relatively large robust stomach worms that accumulate in hosts resulting in high worm burdens. To ascertain whether the presence of spirurid worms or their burdens alters the host's likelihood of infection with other helminth species, we analysed a database containing quantitative data on helminth parasites of these mice (n = 431). This comprised of worm burdens recorded during 4 surveys, conducted at 4-year intervals, in 4 wadis, during late summer of each year. The presence of spirurid worms did not significantly alter species richness with other helminth species nor the likelihood of mice carrying other nematode species. However, there was a significant association, particularly of P. muricola, with the presence of intestinal stages of cestodes, and with the acanthocephalan Moniliformis acomysi. After controlling for intrinsic and extrinsic factors, mice harbouring spirurid worms had greater worm burdens of other helminths compared with mice without spirurids. Moreover, spirurid worm burdens showed a significant positive covariation with similarly adjusted species richness of other helminths, non-spirurid helminths, non-spirurid nematodes, oxyuroid nematodes and intestinal stage cestode worm burdens. We interpret these results as an indication that the key driver for co-occurrence of spirurids with other helminths is likely to be transmission via common arthropod hosts (for cestodes and acanthocephalans), but also that mice carrying the heavier spirurid worm burdens become more susceptible to directly transmitted nematodes such as the Oxyuroidea.
format Article
id doaj-art-d12e153d8bc347d784ee4fe2735ea68f
institution Kabale University
issn 0031-1820
1469-8161
language English
publishDate 2024-07-01
publisher Cambridge University Press
record_format Article
series Parasitology
spelling doaj-art-d12e153d8bc347d784ee4fe2735ea68f2024-11-15T13:59:24ZengCambridge University PressParasitology0031-18201469-81612024-07-0115180882010.1017/S0031182024000891Large-bodied gastric spirurids (Nematoda, Spirurida) predict structure in the downstream gastrointestinal helminth community of wild spiny mice (Acomys dimidiatus)Jerzy M. Behnke0https://orcid.org/0000-0001-9396-2572Joseph A. Jackson1https://orcid.org/0000-0003-0330-5478Francis Gilbert2Eman M. E. Mohallal3Anna Bajer4https://orcid.org/0000-0001-6199-8458School of Life Sciences, University of Nottingham, University Park, Nottingham NG7 2RD, UKSchool of Science, Engineering and Environment, University of Salford, Manchester M5 4WT, UKSchool of Life Sciences, University of Nottingham, University Park, Nottingham NG7 2RD, UKThe Ecology Unit of Desert Animals, Desert Research Centre, 1 Mataf El Matareya St, El Matareya, Cairo, EgyptDepartment of Eco-Epidemiology of Parasitic Diseases, Faculty of Biology, Institute of Developmental Biology and Biomedical Sciences, University of Warsaw, Miecznikowa 1, 02-096 Warsaw, PolandThe dominant helminths infecting spiny mice (Acomys dimidiatus) in the montane wadis of the Sinai Peninsula of Egypt are spirurid nematodes, notably Protospirura muricola and Mastophorus muris. Both are relatively large robust stomach worms that accumulate in hosts resulting in high worm burdens. To ascertain whether the presence of spirurid worms or their burdens alters the host's likelihood of infection with other helminth species, we analysed a database containing quantitative data on helminth parasites of these mice (n = 431). This comprised of worm burdens recorded during 4 surveys, conducted at 4-year intervals, in 4 wadis, during late summer of each year. The presence of spirurid worms did not significantly alter species richness with other helminth species nor the likelihood of mice carrying other nematode species. However, there was a significant association, particularly of P. muricola, with the presence of intestinal stages of cestodes, and with the acanthocephalan Moniliformis acomysi. After controlling for intrinsic and extrinsic factors, mice harbouring spirurid worms had greater worm burdens of other helminths compared with mice without spirurids. Moreover, spirurid worm burdens showed a significant positive covariation with similarly adjusted species richness of other helminths, non-spirurid helminths, non-spirurid nematodes, oxyuroid nematodes and intestinal stage cestode worm burdens. We interpret these results as an indication that the key driver for co-occurrence of spirurids with other helminths is likely to be transmission via common arthropod hosts (for cestodes and acanthocephalans), but also that mice carrying the heavier spirurid worm burdens become more susceptible to directly transmitted nematodes such as the Oxyuroidea.https://www.cambridge.org/core/product/identifier/S0031182024000891/type/journal_articleAcanthocephalaAcomys dimidiatusarthropod-mediated transmissionassociations and interactions between helminth speciesCestodaNematodaOxyuroideaspiny miceSpirurida
spellingShingle Jerzy M. Behnke
Joseph A. Jackson
Francis Gilbert
Eman M. E. Mohallal
Anna Bajer
Large-bodied gastric spirurids (Nematoda, Spirurida) predict structure in the downstream gastrointestinal helminth community of wild spiny mice (Acomys dimidiatus)
Parasitology
Acanthocephala
Acomys dimidiatus
arthropod-mediated transmission
associations and interactions between helminth species
Cestoda
Nematoda
Oxyuroidea
spiny mice
Spirurida
title Large-bodied gastric spirurids (Nematoda, Spirurida) predict structure in the downstream gastrointestinal helminth community of wild spiny mice (Acomys dimidiatus)
title_full Large-bodied gastric spirurids (Nematoda, Spirurida) predict structure in the downstream gastrointestinal helminth community of wild spiny mice (Acomys dimidiatus)
title_fullStr Large-bodied gastric spirurids (Nematoda, Spirurida) predict structure in the downstream gastrointestinal helminth community of wild spiny mice (Acomys dimidiatus)
title_full_unstemmed Large-bodied gastric spirurids (Nematoda, Spirurida) predict structure in the downstream gastrointestinal helminth community of wild spiny mice (Acomys dimidiatus)
title_short Large-bodied gastric spirurids (Nematoda, Spirurida) predict structure in the downstream gastrointestinal helminth community of wild spiny mice (Acomys dimidiatus)
title_sort large bodied gastric spirurids nematoda spirurida predict structure in the downstream gastrointestinal helminth community of wild spiny mice acomys dimidiatus
topic Acanthocephala
Acomys dimidiatus
arthropod-mediated transmission
associations and interactions between helminth species
Cestoda
Nematoda
Oxyuroidea
spiny mice
Spirurida
url https://www.cambridge.org/core/product/identifier/S0031182024000891/type/journal_article
work_keys_str_mv AT jerzymbehnke largebodiedgastricspiruridsnematodaspiruridapredictstructureinthedownstreamgastrointestinalhelminthcommunityofwildspinymiceacomysdimidiatus
AT josephajackson largebodiedgastricspiruridsnematodaspiruridapredictstructureinthedownstreamgastrointestinalhelminthcommunityofwildspinymiceacomysdimidiatus
AT francisgilbert largebodiedgastricspiruridsnematodaspiruridapredictstructureinthedownstreamgastrointestinalhelminthcommunityofwildspinymiceacomysdimidiatus
AT emanmemohallal largebodiedgastricspiruridsnematodaspiruridapredictstructureinthedownstreamgastrointestinalhelminthcommunityofwildspinymiceacomysdimidiatus
AT annabajer largebodiedgastricspiruridsnematodaspiruridapredictstructureinthedownstreamgastrointestinalhelminthcommunityofwildspinymiceacomysdimidiatus