Insights into the Mode of Action of Novel Morpholinated Curcumin Derivatives Exhibiting Potent Antitumor Activity in Bladder Cancer Cells In Vitro

Insights into the Mode of Action of Novel Morpholinated Curcumin Derivatives Exhibiting Potent Antitumor Activity in Bladder Cancer Cells In Vitro

Although curcumin is a well-known natural polyphenol with many biological activities, its clinical application has been limited by low aqueous solubility and stability. Therefore, curcumin derivatives have been proposed to overcome these limitations and increase anticancer activity. This study teste...

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Bibliographic Details
Main Authors: Paulina Kobylka, Pawel Bakun, Joanna Kuzminska, Tomasz Goslinski, Marek Murias, Malgorzata Kucinska
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Molecules
Subjects:
curcumin
curcumin derivatives
apoptosis
bladder cancer
hypoxia
cancer research
Online Access:https://www.mdpi.com/1420-3049/30/2/295
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