Malignant breast adenomyoepithelioma: case report and literature review

Malignant adenomyoepithelioma (MAME) of the breast is a rare tumor with both benign and malignant features. We report a case of a 67-year-old woman who presented with a mass in the outer quadrant of the right breast, detected during a routine check-up. The mass was classified as BI-RADS 3. After min...

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Main Authors: Jinxiu Ma, Gang Zhao, Mingchao Bi, Xiaoxiao Dong, Jian Sun, Xiaozhen Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2024.1525050/full
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author Jinxiu Ma
Gang Zhao
Mingchao Bi
Xiaoxiao Dong
Jian Sun
Xiaozhen Wang
author_facet Jinxiu Ma
Gang Zhao
Mingchao Bi
Xiaoxiao Dong
Jian Sun
Xiaozhen Wang
author_sort Jinxiu Ma
collection DOAJ
description Malignant adenomyoepithelioma (MAME) of the breast is a rare tumor with both benign and malignant features. We report a case of a 67-year-old woman who presented with a mass in the outer quadrant of the right breast, detected during a routine check-up. The mass was classified as BI-RADS 3. After minimally invasive excision, pathology confirmed low-grade malignant adenomyoepithelioma. The patient then underwent total mastectomy and sentinel lymph node biopsy (SLNB). At two years of follow-up, there was no recurrence or metastasis. This case highlights the rarity of MAME and the importance of early diagnosis and complete excision.
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institution Kabale University
issn 2296-858X
language English
publishDate 2025-01-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Medicine
spelling doaj-art-d10154c61c1f4678ac6d97ae120a57fd2025-01-15T06:10:25ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-01-011110.3389/fmed.2024.15250501525050Malignant breast adenomyoepithelioma: case report and literature reviewJinxiu Ma0Gang Zhao1Mingchao Bi2Xiaoxiao Dong3Jian Sun4Xiaozhen Wang5Department of Breast Surgery, General Surgery Center, The First Hospital of Jilin University, Changchun, ChinaDepartment of Breast Surgery, General Surgery Center, The First Hospital of Jilin University, Changchun, ChinaDepartment of Ophthalmology, The First Hospital of Jilin University, Changchun, ChinaDepartment of Breast Surgery, General Surgery Center, The First Hospital of Jilin University, Changchun, ChinaDepartment of Breast Surgery, General Surgery Center, The First Hospital of Jilin University, Changchun, ChinaDepartment of Breast Surgery, General Surgery Center, The First Hospital of Jilin University, Changchun, ChinaMalignant adenomyoepithelioma (MAME) of the breast is a rare tumor with both benign and malignant features. We report a case of a 67-year-old woman who presented with a mass in the outer quadrant of the right breast, detected during a routine check-up. The mass was classified as BI-RADS 3. After minimally invasive excision, pathology confirmed low-grade malignant adenomyoepithelioma. The patient then underwent total mastectomy and sentinel lymph node biopsy (SLNB). At two years of follow-up, there was no recurrence or metastasis. This case highlights the rarity of MAME and the importance of early diagnosis and complete excision.https://www.frontiersin.org/articles/10.3389/fmed.2024.1525050/fulladenomyoepitheliomabreast cancerdiagnosistreatment strategiespathology
spellingShingle Jinxiu Ma
Gang Zhao
Mingchao Bi
Xiaoxiao Dong
Jian Sun
Xiaozhen Wang
Malignant breast adenomyoepithelioma: case report and literature review
Frontiers in Medicine
adenomyoepithelioma
breast cancer
diagnosis
treatment strategies
pathology
title Malignant breast adenomyoepithelioma: case report and literature review
title_full Malignant breast adenomyoepithelioma: case report and literature review
title_fullStr Malignant breast adenomyoepithelioma: case report and literature review
title_full_unstemmed Malignant breast adenomyoepithelioma: case report and literature review
title_short Malignant breast adenomyoepithelioma: case report and literature review
title_sort malignant breast adenomyoepithelioma case report and literature review
topic adenomyoepithelioma
breast cancer
diagnosis
treatment strategies
pathology
url https://www.frontiersin.org/articles/10.3389/fmed.2024.1525050/full
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AT gangzhao malignantbreastadenomyoepitheliomacasereportandliteraturereview
AT mingchaobi malignantbreastadenomyoepitheliomacasereportandliteraturereview
AT xiaoxiaodong malignantbreastadenomyoepitheliomacasereportandliteraturereview
AT jiansun malignantbreastadenomyoepitheliomacasereportandliteraturereview
AT xiaozhenwang malignantbreastadenomyoepitheliomacasereportandliteraturereview