CD19+CD11c+T-bet+ B cells in myasthenia gravis: a potential biomarker

CD19+CD11c+T-bet+ B cells in myasthenia gravis: a potential biomarker

BackgroundMyasthenia gravis (MG), an autoimmune disorder characterized by B cell-driven autoantibody production, exhibits heterogeneous B cell subsets dysregulation and incompletely defined signaling mechanisms.MethodsA cohort of 20 naïve MG patients positive for anti-acetylcholine receptor (AChR) a...

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Bibliographic Details
Main Authors: Yaru Lu, Huimin Shen, Yiye Wang, Kai Ma, Ruihua Sun, Ying Zhao, Yaqiong Li, Qian Ma, Jiewen Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Neurology
Subjects:
myasthenia gravis
NF-κB pathway
age-associated B cells
proteomics
flow cytometry
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2025.1623066/full
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https://www.frontiersin.org/articles/10.3389/fneur.2025.1623066/full

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