Predictors and classifications of the degree of severity of acute pancreatitis

Severe acute panreatitis is a life-threatening disease with mortality rates of about 15%. With the development of infected necrotizing pancreatitis, complicated by the development of organ failure, the mortality rate is 35.2%. Due to the fact that acute pancreatitis is a highly variable pathological...

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Main Authors: A. V. Fedorov, V. N. Ektov, M. A. Khodorkovskiy
Format: Article
Language:Russian
Published: Pavlov First Saint Petersburg State Medical University 2023-03-01
Series:Вестник хирургии имени И.И. Грекова
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Online Access:https://www.vestnik-grekova.ru/jour/article/view/1804
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author A. V. Fedorov
V. N. Ektov
M. A. Khodorkovskiy
author_facet A. V. Fedorov
V. N. Ektov
M. A. Khodorkovskiy
author_sort A. V. Fedorov
collection DOAJ
description Severe acute panreatitis is a life-threatening disease with mortality rates of about 15%. With the development of infected necrotizing pancreatitis, complicated by the development of organ failure, the mortality rate is 35.2%. Due to the fact that acute pancreatitis is a highly variable pathological process, leading to a wide range of clinical outcomes, predicting the severity of the disease and early identification of patients at risk of developing severe complications is critical to optimize treatment outcomes for this disease. Currently, there are no uniquely accurate and practically available laboratory tests to predict the severity of patients with acute pancreatitis. The review presents literature data on the terminology and classifications of the severity of acute pancreatitis, taking into account the possibilities of their practical application. Information on clinical scale systems for assessing the severity of acute pancreatitis with an assessment of their effectiveness in predicting various treatment outcomes is presented in detail. The characteristics and capabilities of various laboratory markers in the assessment of organ failure and diagnosis of systemic complications of acute pancreatitis are presented. Currently, for the best assessment of the severity of acute pancreatitis, it is necessary to use a multidisciplinary clinical examination of patients and a combination of various predictive tools.
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series Вестник хирургии имени И.И. Грекова
spelling doaj-art-d0e53824358a477c85600fa35d0c08e02024-11-26T10:43:56ZrusPavlov First Saint Petersburg State Medical UniversityВестник хирургии имени И.И. Грекова0042-46252023-03-01181310010710.24884/0042-4625-2022-181-3-100-1071395Predictors and classifications of the degree of severity of acute pancreatitisA. V. Fedorov0V. N. Ektov1M. A. Khodorkovskiy2Yevdokimov Moscow State University of Medicine and DentistryBurdenko Voronezh State Medical UniversityBurdenko Voronezh State Medical UniversitySevere acute panreatitis is a life-threatening disease with mortality rates of about 15%. With the development of infected necrotizing pancreatitis, complicated by the development of organ failure, the mortality rate is 35.2%. Due to the fact that acute pancreatitis is a highly variable pathological process, leading to a wide range of clinical outcomes, predicting the severity of the disease and early identification of patients at risk of developing severe complications is critical to optimize treatment outcomes for this disease. Currently, there are no uniquely accurate and practically available laboratory tests to predict the severity of patients with acute pancreatitis. The review presents literature data on the terminology and classifications of the severity of acute pancreatitis, taking into account the possibilities of their practical application. Information on clinical scale systems for assessing the severity of acute pancreatitis with an assessment of their effectiveness in predicting various treatment outcomes is presented in detail. The characteristics and capabilities of various laboratory markers in the assessment of organ failure and diagnosis of systemic complications of acute pancreatitis are presented. Currently, for the best assessment of the severity of acute pancreatitis, it is necessary to use a multidisciplinary clinical examination of patients and a combination of various predictive tools.https://www.vestnik-grekova.ru/jour/article/view/1804acute necrotizing pancreatitisclinical scoring systems
spellingShingle A. V. Fedorov
V. N. Ektov
M. A. Khodorkovskiy
Predictors and classifications of the degree of severity of acute pancreatitis
Вестник хирургии имени И.И. Грекова
acute necrotizing pancreatitis
clinical scoring systems
title Predictors and classifications of the degree of severity of acute pancreatitis
title_full Predictors and classifications of the degree of severity of acute pancreatitis
title_fullStr Predictors and classifications of the degree of severity of acute pancreatitis
title_full_unstemmed Predictors and classifications of the degree of severity of acute pancreatitis
title_short Predictors and classifications of the degree of severity of acute pancreatitis
title_sort predictors and classifications of the degree of severity of acute pancreatitis
topic acute necrotizing pancreatitis
clinical scoring systems
url https://www.vestnik-grekova.ru/jour/article/view/1804
work_keys_str_mv AT avfedorov predictorsandclassificationsofthedegreeofseverityofacutepancreatitis
AT vnektov predictorsandclassificationsofthedegreeofseverityofacutepancreatitis
AT makhodorkovskiy predictorsandclassificationsofthedegreeofseverityofacutepancreatitis