Urinary and plasma donor-derived cell-free DNA for noninvasive monitoring of BK polyomavirus-associated nephropathy in kidney transplant recipients: a prospective cohort study

Urinary and plasma donor-derived cell-free DNA for noninvasive monitoring of BK polyomavirus-associated nephropathy in kidney transplant recipients: a prospective cohort study

Background BK polyomavirus-associated nephropathy (BKPyVAN) is a major cause of allograft injury and dysfunction in kidney transplant recipients. Current monitoring tools, including viremia and biopsy, have limitations in sensitivity, invasiveness, and timing.Objective To evaluate donor-derived cell...

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Main Authors: Luying Guo, Sulin Luo, Rongfang Shen, Pengpeng Yan, Meifang Wang, Tianlu Zhang, Junhao Lv, Guangjun Liu, Hongfeng Huang, Zhimin Chen, Huiping Wang, Wenhan Peng, Jianyong Wu, Jianghua Chen, Rending Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Renal Failure
Subjects:
BKPyVAN
kidney transplantation
donor-derived cell-free DNA
allograft rejection
dynamic surveillance
Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2025.2521452
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