Advances in nanocarrier technology for drug encapsulation: a comprehensive overview
Abstract Nanotechnology has paved path to improve solubility, release pattern, bioavailability and targeted efficacy of most of the BCS class drugs as nanocarriers. The nanocarriers may be classified as magnetic, solid lipid (SLN’s), dendrimers, liposomes, and nanostructured lipid carriers. Advances...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-07-01
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| Series: | Discover Materials |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s43939-025-00271-1 |
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| Summary: | Abstract Nanotechnology has paved path to improve solubility, release pattern, bioavailability and targeted efficacy of most of the BCS class drugs as nanocarriers. The nanocarriers may be classified as magnetic, solid lipid (SLN’s), dendrimers, liposomes, and nanostructured lipid carriers. Advances in design of formulation using nanocarriers enhance biocompatibility with more functional surfaces and targeted delivery. The methodological survey was conducted from various search engines such as Scopus, Web of science, Science direct, Pubmed to collect 72 relevant articles that benefit the review with nanocarrier encapsulation and its method. This review discusses nanostructured lipid carriers (NLC), solid lipid nanoparticles (SLN), from physical encapsulation, and magnetic nanoparticles (MNP) from physical adsorption approaches. The final bibliometric dataset was then constructed using 42 papers spanning 2013– 2024 including recent developments. While the article written by Khan et al. in 2020 is considered the most impactful publication that emphasized on precise particle size and loading efficacy, Shah AA is recognized as the author with the highest publication output emphasized on regulatory hurdles, stability and controlled release nature of nanomodification. Nanocarrier technology for drug encapsulation along with limitations such as toxicity, scalability and regulatory hurdles is explained in broad strokes by these outcomes. Graphical Abstract |
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| ISSN: | 2730-7727 |