Celastrol attenuates Alzheimer’s disease-mediated learning and memory impairment by inhibiting endoplasmic reticulum stress-induced inflammation and oxidative stress

Celastrol attenuates Alzheimer’s disease-mediated learning and memory impairment by inhibiting endoplasmic reticulum stress-induced inflammation and oxidative stress

Introduction Alzheimer’s disease (AD) is triggered by biological mechanisms such as neuroinflammation and oxidative stress. Endoplasmic reticulum (ER) stress can lead to the expression of molecular chaperones in the ER, which helps in restoring cellular homeostasis. Researchers have highlighted the...

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Bibliographic Details
Main Authors: Fanfan Cao, Limin Xu, Xiaoxue He, Yongbin Chi, Ying Wang, Qiuyun Liu, Denghai Zhang
Format: Article
Language:English
Published: Termedia Publishing House 2024-06-01
Series:Archives of Medical Science
Subjects:
alzheimer’s disease
celastrol
endoplasmic reticulum stress
inflammation
oxidative stress
Online Access:https://www.archivesofmedicalscience.com/Celastrol-attenuates-Alzheimer-s-disease-mediated-learning-and-memory-impairment,189906,0,2.html
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