Aspiration of acidified milk induces milk allergy by activating alveolar macrophages in mice

Aspiration of acidified milk induces milk allergy by activating alveolar macrophages in mice

Background: Epidemiological studies have identified associations between gastroesophageal reflux (GER) and cow's milk allergy (CMA) in infants. However, the role of GER in the development of CMA remains poorly understood. Our primary objectives were to develop a mouse model that suggests GER as...

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Bibliographic Details
Main Authors: Akiko Nakaoka, Takayasu Nomura, Atsushi Suzuki, Kazuyoshi Ozeki, Hirohito Kita, Shinji Saitoh
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Allergology International
Subjects:
Airway sensitization
Cow's milk allergy
Gastroesophageal reflux
Innate immunity
Toll-like receptor 4
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893024000820
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