Prospects of marine-derived compounds as potential therapeutic agents for glioma
Context Glioma, the most common primary malignant brain tumour, is a grave health concern associated with high morbidity and mortality. Current treatments, while effective to some extent, are often hindered by factors such as the blood–brain barrier and tumour microenvironment. This underscores the...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2024-12-01
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| Series: | Pharmaceutical Biology |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/13880209.2024.2359659 |
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| _version_ | 1846136277321121792 |
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| author | Ying Liu Zhiyang Zhou Shusen Sun |
| author_facet | Ying Liu Zhiyang Zhou Shusen Sun |
| author_sort | Ying Liu |
| collection | DOAJ |
| description | Context Glioma, the most common primary malignant brain tumour, is a grave health concern associated with high morbidity and mortality. Current treatments, while effective to some extent, are often hindered by factors such as the blood–brain barrier and tumour microenvironment. This underscores the pressing need for exploring new pharmacologically active anti-glioma compounds.Methods This review synthesizes information from major databases, including Chemical Abstracts, Medicinal and Aromatic Plants Abstracts, ScienceDirect, SciFinder, Google Scholar, Scopus, PubMed, Springer Link and relevant books. Publications were selected without date restrictions, using terms such as ‘Hymenocrater spp.,’ ‘phytochemical,’ ‘pharmacological,’ ‘extract,’ ‘essential oil’ and ‘traditional uses.’ General web searches using Google and Yahoo were also performed. Articles related to agriculture, ecology, synthetic work or published in languages other than English or Chinese were excluded.Results The marine environment has been identified as a rich source of diverse natural products with potent antitumour properties.Conclusions This paper not only provides a comprehensive review of marine-derived compounds but also unveils their potential in treating glioblastoma multiforme (GBM) based on functional classifications. It encapsulates the latest research progress on the regulatory biological functions and mechanisms of these marine substances in GBM, offering invaluable insights for the development of new glioma treatments. |
| format | Article |
| id | doaj-art-d0529e4436d94f76aabf3503f06bc904 |
| institution | Kabale University |
| issn | 1388-0209 1744-5116 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Pharmaceutical Biology |
| spelling | doaj-art-d0529e4436d94f76aabf3503f06bc9042024-12-09T07:41:45ZengTaylor & Francis GroupPharmaceutical Biology1388-02091744-51162024-12-0162151352610.1080/13880209.2024.2359659Prospects of marine-derived compounds as potential therapeutic agents for gliomaYing Liu0Zhiyang Zhou1Shusen Sun2Department of Pathology, Xiangya Changde Hospital, Changde, ChinaDepartment of Breast Surgery, Xiangya Hospital, Central South University, Changsha, ChinaCollege of Pharmacy and Health Sciences, Western New England University, Springfield, MA, USAContext Glioma, the most common primary malignant brain tumour, is a grave health concern associated with high morbidity and mortality. Current treatments, while effective to some extent, are often hindered by factors such as the blood–brain barrier and tumour microenvironment. This underscores the pressing need for exploring new pharmacologically active anti-glioma compounds.Methods This review synthesizes information from major databases, including Chemical Abstracts, Medicinal and Aromatic Plants Abstracts, ScienceDirect, SciFinder, Google Scholar, Scopus, PubMed, Springer Link and relevant books. Publications were selected without date restrictions, using terms such as ‘Hymenocrater spp.,’ ‘phytochemical,’ ‘pharmacological,’ ‘extract,’ ‘essential oil’ and ‘traditional uses.’ General web searches using Google and Yahoo were also performed. Articles related to agriculture, ecology, synthetic work or published in languages other than English or Chinese were excluded.Results The marine environment has been identified as a rich source of diverse natural products with potent antitumour properties.Conclusions This paper not only provides a comprehensive review of marine-derived compounds but also unveils their potential in treating glioblastoma multiforme (GBM) based on functional classifications. It encapsulates the latest research progress on the regulatory biological functions and mechanisms of these marine substances in GBM, offering invaluable insights for the development of new glioma treatments.https://www.tandfonline.com/doi/10.1080/13880209.2024.2359659Marine environmentnatural productstreatment |
| spellingShingle | Ying Liu Zhiyang Zhou Shusen Sun Prospects of marine-derived compounds as potential therapeutic agents for glioma Pharmaceutical Biology Marine environment natural products treatment |
| title | Prospects of marine-derived compounds as potential therapeutic agents for glioma |
| title_full | Prospects of marine-derived compounds as potential therapeutic agents for glioma |
| title_fullStr | Prospects of marine-derived compounds as potential therapeutic agents for glioma |
| title_full_unstemmed | Prospects of marine-derived compounds as potential therapeutic agents for glioma |
| title_short | Prospects of marine-derived compounds as potential therapeutic agents for glioma |
| title_sort | prospects of marine derived compounds as potential therapeutic agents for glioma |
| topic | Marine environment natural products treatment |
| url | https://www.tandfonline.com/doi/10.1080/13880209.2024.2359659 |
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