Effect of Right Median Nerve Stimulation on Clinical Efficacy and Prognosis of Patients with Consciousness Disorder Caused by Traumatic Brain Injury

Objective:To investigate the clinical effect of right median nerve stimulation on consciousness disorder caused by traumatic brain injury and its influence on prognosis.Methods:A total of 92 patients were divided into control group and experimental group according to random number table method, with...

Full description

Saved in:
Bibliographic Details
Main Authors: Kun ZHAO, Aixian LIU
Format: Article
Language:English
Published: Editorial Office of Rehabilitation Medicine 2020-06-01
Series:康复学报
Subjects:
Online Access:http://kfxb.publish.founderss.cn/thesisDetails#10.3724/SP.J.1329.2020.03005
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1841537058536947712
author Kun ZHAO
Aixian LIU
author_facet Kun ZHAO
Aixian LIU
author_sort Kun ZHAO
collection DOAJ
description Objective:To investigate the clinical effect of right median nerve stimulation on consciousness disorder caused by traumatic brain injury and its influence on prognosis.Methods:A total of 92 patients were divided into control group and experimental group according to random number table method, with 46 cases in each group. The control group was given conventional wake-up promotion therapy, while the experimental group was given right median nerve stimulation therapy on the basis of that in the control group. The levels of neurotransmitters, cerebral hemodynamics, clinical scores, adverse reactions and prognosis before and after treatment were compared between the two groups.Results:Before treatment, there was no significant difference in neurotransmitter level, cerebral hemodynamics and clinical score between the two groups (<italic>P</italic>&gt;0.05). After treatment, norepinephrine (NE), dopamine (DA), mean blood flow velocity (VM), blood flow velocity (VS), electroencephalogram (EEG) score, auditory brainstem response (ABR), and Glasgow Coma Scale (GCS) increased in both groups (<italic>P</italic>&lt;0.05), and the above indexes in the experimental group were higher than those in the control group (<italic>P</italic>&lt;0.05). The β-endorphin (β-EP) and pulsatility index (PI) of the two groups decreased (<italic>P</italic>&lt;0.05), while that of the experimental group was lower than that of the control group, with statistically significant difference (<italic>P</italic>&lt;0.05). There was no significant difference in the incidence of adverse reactions between the two groups (<italic>P</italic>&gt;0.05). The prognosis of the experimental group was better than that of the control group (<italic>P</italic>&lt;0.05).Conclusion:Right median nerve stimulation has a positive wake-up promoting effect on patients with consciousness disorders caused by traumatic brain injury. It can regulate neurotransmitter release, improve cerebral blood flow and brain electrical activity, and reduce disability rate.
format Article
id doaj-art-d02aa2059f55430fb48a5c359e8afc4c
institution Kabale University
issn 2096-0328
language English
publishDate 2020-06-01
publisher Editorial Office of Rehabilitation Medicine
record_format Article
series 康复学报
spelling doaj-art-d02aa2059f55430fb48a5c359e8afc4c2025-01-14T10:03:50ZengEditorial Office of Rehabilitation Medicine康复学报2096-03282020-06-013019219623131848Effect of Right Median Nerve Stimulation on Clinical Efficacy and Prognosis of Patients with Consciousness Disorder Caused by Traumatic Brain InjuryKun ZHAOAixian LIUObjective:To investigate the clinical effect of right median nerve stimulation on consciousness disorder caused by traumatic brain injury and its influence on prognosis.Methods:A total of 92 patients were divided into control group and experimental group according to random number table method, with 46 cases in each group. The control group was given conventional wake-up promotion therapy, while the experimental group was given right median nerve stimulation therapy on the basis of that in the control group. The levels of neurotransmitters, cerebral hemodynamics, clinical scores, adverse reactions and prognosis before and after treatment were compared between the two groups.Results:Before treatment, there was no significant difference in neurotransmitter level, cerebral hemodynamics and clinical score between the two groups (<italic>P</italic>&gt;0.05). After treatment, norepinephrine (NE), dopamine (DA), mean blood flow velocity (VM), blood flow velocity (VS), electroencephalogram (EEG) score, auditory brainstem response (ABR), and Glasgow Coma Scale (GCS) increased in both groups (<italic>P</italic>&lt;0.05), and the above indexes in the experimental group were higher than those in the control group (<italic>P</italic>&lt;0.05). The β-endorphin (β-EP) and pulsatility index (PI) of the two groups decreased (<italic>P</italic>&lt;0.05), while that of the experimental group was lower than that of the control group, with statistically significant difference (<italic>P</italic>&lt;0.05). There was no significant difference in the incidence of adverse reactions between the two groups (<italic>P</italic>&gt;0.05). The prognosis of the experimental group was better than that of the control group (<italic>P</italic>&lt;0.05).Conclusion:Right median nerve stimulation has a positive wake-up promoting effect on patients with consciousness disorders caused by traumatic brain injury. It can regulate neurotransmitter release, improve cerebral blood flow and brain electrical activity, and reduce disability rate.http://kfxb.publish.founderss.cn/thesisDetails#10.3724/SP.J.1329.2020.03005traumatic brain injuryawareness disorderright median nerve stimulationprognosis
spellingShingle Kun ZHAO
Aixian LIU
Effect of Right Median Nerve Stimulation on Clinical Efficacy and Prognosis of Patients with Consciousness Disorder Caused by Traumatic Brain Injury
康复学报
traumatic brain injury
awareness disorder
right median nerve stimulation
prognosis
title Effect of Right Median Nerve Stimulation on Clinical Efficacy and Prognosis of Patients with Consciousness Disorder Caused by Traumatic Brain Injury
title_full Effect of Right Median Nerve Stimulation on Clinical Efficacy and Prognosis of Patients with Consciousness Disorder Caused by Traumatic Brain Injury
title_fullStr Effect of Right Median Nerve Stimulation on Clinical Efficacy and Prognosis of Patients with Consciousness Disorder Caused by Traumatic Brain Injury
title_full_unstemmed Effect of Right Median Nerve Stimulation on Clinical Efficacy and Prognosis of Patients with Consciousness Disorder Caused by Traumatic Brain Injury
title_short Effect of Right Median Nerve Stimulation on Clinical Efficacy and Prognosis of Patients with Consciousness Disorder Caused by Traumatic Brain Injury
title_sort effect of right median nerve stimulation on clinical efficacy and prognosis of patients with consciousness disorder caused by traumatic brain injury
topic traumatic brain injury
awareness disorder
right median nerve stimulation
prognosis
url http://kfxb.publish.founderss.cn/thesisDetails#10.3724/SP.J.1329.2020.03005
work_keys_str_mv AT kunzhao effectofrightmediannervestimulationonclinicalefficacyandprognosisofpatientswithconsciousnessdisordercausedbytraumaticbraininjury
AT aixianliu effectofrightmediannervestimulationonclinicalefficacyandprognosisofpatientswithconsciousnessdisordercausedbytraumaticbraininjury