Optimization of meropenem continuous infusion based on Monte Carlo simulation integrating with degradation study.

Optimization of meropenem continuous infusion based on Monte Carlo simulation integrating with degradation study.

<h4>Objective</h4>Meropenem degradation poses a challenge to continuous infusion (CI) implementation. However, data about the impact of degradation on the probability of target attainment (PTA) of meropenem has been limited. This study evaluated the stability of meropenem brands and the...

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Main Authors: Nguyen Tran Nam Tien, Vu Ngan Binh, Pham Thi Thanh Ha, Dang Thi Ngoc Lan, Yong-Soon Cho, Nguyen Phuoc Long, Jae-Gook Shin, Nguyen Hoang Anh, Truong Anh Quan, Do Ngoc Tuan, Nguyen Khac Tiep, Pham The Thach, Vu Dinh Hoa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0313764
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