Role of tubular cell-derived exosomes in renal ischemia reperfusion injury
Renal ischemia reperfusion injury refers to a pathophysiological phenomenon that aggravates the degree of renal injury due to the restoration of blood supply after transient ischemia of renal tissue. It has been found that renal tubular cell-derived exosomes alleviate renal ischemia reperfusion inju...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | zho |
| Published: |
Editorial Department of Journal of Clinical Nephrology
2024-11-01
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| Series: | Linchuang shenzangbing zazhi |
| Subjects: | |
| Online Access: | http://www.lcszb.com/cn/article/doi/10.3969/j.issn.1671-2390.2024.11.009 |
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| Summary: | Renal ischemia reperfusion injury refers to a pathophysiological phenomenon that aggravates the degree of renal injury due to the restoration of blood supply after transient ischemia of renal tissue. It has been found that renal tubular cell-derived exosomes alleviate renal ischemia reperfusion injury through anti-inflammatory, antioxidant, inhibition of apoptosis, promotion of tissue regeneration and activation of autophagy . This review will discuss the protective effect of tubular cell-derived exosomes on renal ischemia reperfusion injury, in order to provide a theoretical basis for the clinical diagnosis, treatment and early prevention of renal ischemia reperfusion injury. |
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| ISSN: | 1671-2390 |