Challenges of continuation of live liver donor programme during COVID-19 pandemic in Pakistan: outcomes and lessons learned
Background COVID-19 pandemic has globally affected healthcare including the transplantation programmes.Materials and methods We retrospectively studied the impact of COVID-19 on live liver donor (LLD) programme at liver transplant centre in Gambat, Pakistan. Standard operative procedures (SOPs) incl...
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| Format: | Article |
| Language: | English |
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BMJ Publishing Group
2021-10-01
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| Series: | BMJ Open Gastroenterology |
| Online Access: | https://bmjopengastro.bmj.com/content/8/1/e000723.full |
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| author | Azhar Hussain Bilal Ahmed Abdul Wahab Dogar Shams Uddin Syed Hasnain Abbas Hala Izzo Kaleem Ullah Azam Shoaib Siraj Ud Din Muhammad Ameer Hamza Munaza Zafar Muhammad Affan Qaiser Hamid Raza Muhammad Asif Baig Ali Husnain Khalid Mumtaz |
| author_facet | Azhar Hussain Bilal Ahmed Abdul Wahab Dogar Shams Uddin Syed Hasnain Abbas Hala Izzo Kaleem Ullah Azam Shoaib Siraj Ud Din Muhammad Ameer Hamza Munaza Zafar Muhammad Affan Qaiser Hamid Raza Muhammad Asif Baig Ali Husnain Khalid Mumtaz |
| author_sort | Azhar Hussain |
| collection | DOAJ |
| description | Background COVID-19 pandemic has globally affected healthcare including the transplantation programmes.Materials and methods We retrospectively studied the impact of COVID-19 on live liver donor (LLD) programme at liver transplant centre in Gambat, Pakistan. Standard operative procedures (SOPs) including COVID-19 nasopharyngeal swab PCR, CT scans, personal protective equipment use, 6-feet distancing were developed for LLD and transplant team to mitigate COVID-19 exposure. We compared the complications, healthcare utilisation (hospital stay, readmission) and mortality between two LLD cohorts—before and during COVID-19 pandemic from March 2019 to December 2020.Results During study period 300 LLD surgeries were performed. There was an increase in rate of LLDs from 132 (44%) in pre-COVID to 168 (56%) during COVID-19 era. Average numbers of transplants per month performed during pre-COVID and during COVID-19 era were 10.1 and 14, respectively. No donor has developed COVID-19 infection during hospitalisation. Rate of all LLD complications (32 (21.47%) and 49 (29.16%), p=0.43), uneventful discharges (120/168 (71.4%) and 88/132 (66.6%), p<0.05), mean hospital stay (6±2 days and 5±2 days, p=0.17) and readmission (5 (4%) and 3 (1.8%), p=0.43) were similar during the pre-COVID and COVID-19 era. No donor mortality was observed during study period.Conclusion With the implementation of mindful SOPs, rate of LLD increased without any case of COVID-19 infection. Our SOPs were helpful in continuation of LLD programme in a developing country during COVID-19 pandemic. |
| format | Article |
| id | doaj-art-cf6d1569a4f444e996d1ed37d59b2c2d |
| institution | Kabale University |
| issn | 2054-4774 |
| language | English |
| publishDate | 2021-10-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open Gastroenterology |
| spelling | doaj-art-cf6d1569a4f444e996d1ed37d59b2c2d2024-12-07T16:55:16ZengBMJ Publishing GroupBMJ Open Gastroenterology2054-47742021-10-018110.1136/bmjgast-2021-000723Challenges of continuation of live liver donor programme during COVID-19 pandemic in Pakistan: outcomes and lessons learnedAzhar Hussain0Bilal Ahmed1Abdul Wahab Dogar2Shams Uddin3Syed Hasnain Abbas4Hala Izzo5Kaleem Ullah6Azam Shoaib7Siraj Ud Din8Muhammad Ameer Hamza9Munaza Zafar10Muhammad Affan Qaiser11Hamid Raza12Muhammad Asif Baig13Ali Husnain14Khalid Mumtaz15Ameer-ud-Din Medical College of PGMI, Lahore, PakistanLiver Transplant Unit, Gambat Institute of Medical Sciences, Gambat, PakistanDepartment of Liver Transplantation, Pir Abdul Qadir Shah Jeelani Institute of Medical Sciences, Gambat, PakistanLiver Transplant Unit, Gambat Institute of Medical Sciences, Gambat, PakistanLiver Transplant Unit, Gambat Institute of Medical Sciences, Gambat, PakistanLiver Transplant Unit, Gambat Institute of Medical Sciences, Gambat, PakistanDepartment of Liver Transplantation, Pir Abdul Qadir Shah Jeelani Institute of Medical Sciences, Gambat, PakistanDepartment of Liver Transplantation, Pir Abdul Qadir Shah Jeelani Institute of Medical Sciences, Gambat, PakistanLiver Transplant Unit, Gambat Institute of Medical Sciences, Gambat, PakistanLiver Transplant Unit, Gambat Institute of Medical Sciences, Gambat, PakistanLiver Transplant Unit, Gambat Institute of Medical Sciences, Gambat, PakistanLiver Transplant Unit, Gambat Institute of Medical Sciences, Gambat, PakistanLiver Transplant Unit, Gambat Institute of Medical Sciences, Gambat, PakistanLiver Transplant Unit, Gambat Institute of Medical Sciences, Gambat, PakistanLiver Transplant Unit, Gambat Institute of Medical Sciences, Gambat, PakistanOhio State University Foundation, Columbus, Ohio, USABackground COVID-19 pandemic has globally affected healthcare including the transplantation programmes.Materials and methods We retrospectively studied the impact of COVID-19 on live liver donor (LLD) programme at liver transplant centre in Gambat, Pakistan. Standard operative procedures (SOPs) including COVID-19 nasopharyngeal swab PCR, CT scans, personal protective equipment use, 6-feet distancing were developed for LLD and transplant team to mitigate COVID-19 exposure. We compared the complications, healthcare utilisation (hospital stay, readmission) and mortality between two LLD cohorts—before and during COVID-19 pandemic from March 2019 to December 2020.Results During study period 300 LLD surgeries were performed. There was an increase in rate of LLDs from 132 (44%) in pre-COVID to 168 (56%) during COVID-19 era. Average numbers of transplants per month performed during pre-COVID and during COVID-19 era were 10.1 and 14, respectively. No donor has developed COVID-19 infection during hospitalisation. Rate of all LLD complications (32 (21.47%) and 49 (29.16%), p=0.43), uneventful discharges (120/168 (71.4%) and 88/132 (66.6%), p<0.05), mean hospital stay (6±2 days and 5±2 days, p=0.17) and readmission (5 (4%) and 3 (1.8%), p=0.43) were similar during the pre-COVID and COVID-19 era. No donor mortality was observed during study period.Conclusion With the implementation of mindful SOPs, rate of LLD increased without any case of COVID-19 infection. Our SOPs were helpful in continuation of LLD programme in a developing country during COVID-19 pandemic.https://bmjopengastro.bmj.com/content/8/1/e000723.full |
| spellingShingle | Azhar Hussain Bilal Ahmed Abdul Wahab Dogar Shams Uddin Syed Hasnain Abbas Hala Izzo Kaleem Ullah Azam Shoaib Siraj Ud Din Muhammad Ameer Hamza Munaza Zafar Muhammad Affan Qaiser Hamid Raza Muhammad Asif Baig Ali Husnain Khalid Mumtaz Challenges of continuation of live liver donor programme during COVID-19 pandemic in Pakistan: outcomes and lessons learned BMJ Open Gastroenterology |
| title | Challenges of continuation of live liver donor programme during COVID-19 pandemic in Pakistan: outcomes and lessons learned |
| title_full | Challenges of continuation of live liver donor programme during COVID-19 pandemic in Pakistan: outcomes and lessons learned |
| title_fullStr | Challenges of continuation of live liver donor programme during COVID-19 pandemic in Pakistan: outcomes and lessons learned |
| title_full_unstemmed | Challenges of continuation of live liver donor programme during COVID-19 pandemic in Pakistan: outcomes and lessons learned |
| title_short | Challenges of continuation of live liver donor programme during COVID-19 pandemic in Pakistan: outcomes and lessons learned |
| title_sort | challenges of continuation of live liver donor programme during covid 19 pandemic in pakistan outcomes and lessons learned |
| url | https://bmjopengastro.bmj.com/content/8/1/e000723.full |
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