Effect of fecal microbiota transplantation on patients with sporadic amyotrophic lateral sclerosis: a randomized, double-blind, placebo-controlled trial

Effect of fecal microbiota transplantation on patients with sporadic amyotrophic lateral sclerosis: a randomized, double-blind, placebo-controlled trial

Abstract Background Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disorder marked by the progressive loss of motor neurons. Recent insights into ALS pathogenesis underscore the pivotal role of the gut microbiome, prompting an investigation into the potential therapeutic impa...

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Main Authors: Renyi Feng, Qingyong Zhu, Ao Wang, Hanzhen Wang, Jiuqi Wang, Pei Chen, Rui Zhang, Dongxiao Liang, Junfang Teng, Mingming Ma, Xuebing Ding, Xuejing Wang
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Medicine
Subjects:
Amyotrophic lateral sclerosis
Fecal microbiota transplantation
Randomized controlled trial
Online Access:https://doi.org/10.1186/s12916-024-03781-6
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