Effects of Cerasus humilis Composite Rod on Anti-fatigue Capacity and Energy Metabolism in Mice
Objective: To investigate the effects of Cerasus humilis composite rod on fatigue resistance and energy metabolism in mice. Methods: Fifty healthy male mice at 8 weeks of age were randomly divided into 5 groups: Control group, model group, Cerasus humilis composite rod group, positive group and high...
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The editorial department of Science and Technology of Food Industry
2024-12-01
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| Series: | Shipin gongye ke-ji |
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| Online Access: | http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2023120121 |
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| author | Fangrong ZHANG Junmin DU Jianling KANG Wenying MAO Li BAI Caixing WANG |
| author_facet | Fangrong ZHANG Junmin DU Jianling KANG Wenying MAO Li BAI Caixing WANG |
| author_sort | Fangrong ZHANG |
| collection | DOAJ |
| description | Objective: To investigate the effects of Cerasus humilis composite rod on fatigue resistance and energy metabolism in mice. Methods: Fifty healthy male mice at 8 weeks of age were randomly divided into 5 groups: Control group, model group, Cerasus humilis composite rod group, positive group and high-fat group. By establishing a fatigue model of swimming+diet control, after 21 days of continuous feeding, the fatigue, energy metabolism and antioxidant related indexes of mice were detected by climbing poles and exhausting swimming time. Results: Compared with the control group, the climbing time and swimming time of the model group decreased significantly (P<0.01), the contents of lactate, blood urea nitrogen, creatine kinase and malondialdehyde were significantly increased (P<0.01), and serum superoxide dismutase, hepatic Na+-K+-ATPase and Ga2+-Mg2+-ATPase decreased significantly (P<0.05). Compared with the model group, the Cerasus humilis composite rod group and positive group could significantly prolong the time of climbing the pole and the time of swimming to exhaustion, which were 2.1 and 1.8 times that of the model group, and could effectively reduce energy consumption, reduce the accumulation of lactate and blood urea nitrogen (P<0.01, P<0.05), reduce the content of MDA and CK in serum, enhance the activity of SOD enzyme in serum (P<0.01), increase the activities of Na+-K+-ATPase and Ga2+-Mg2+-ATPase in liver (P<0.01), increase the level of ATP content and exert anti-fatigue activity. Conclusion: The composite rod has significant anti-fatigue ability and energy metabolism ability, which can improve the exercise ability level of mice by increasing the pole climbing time and weight-bearing exhaustion swimming time, and alleviate fatigue by reducing energy consumption, increasing energy metabolism, improving exercise endurance and improving antioxidant capacity. |
| format | Article |
| id | doaj-art-cf49926d75544a1e9981b98c4fb56c24 |
| institution | Kabale University |
| issn | 1002-0306 |
| language | zho |
| publishDate | 2024-12-01 |
| publisher | The editorial department of Science and Technology of Food Industry |
| record_format | Article |
| series | Shipin gongye ke-ji |
| spelling | doaj-art-cf49926d75544a1e9981b98c4fb56c242024-12-06T03:28:23ZzhoThe editorial department of Science and Technology of Food IndustryShipin gongye ke-ji1002-03062024-12-01452433934510.13386/j.issn1002-0306.20231201212023120121-24Effects of Cerasus humilis Composite Rod on Anti-fatigue Capacity and Energy Metabolism in MiceFangrong ZHANG0Junmin DU1Jianling KANG2Wenying MAO3Li BAI4Caixing WANG5School of Traditional Chinese Medicine and Food Engineering, Shanxi University of Chinese Medicine,Jinzhong 030619, ChinaSchool of Traditional Chinese Medicine and Food Engineering, Shanxi University of Chinese Medicine,Jinzhong 030619, ChinaAccounting Center of Shanxi Forestry and Grassland Bureau, Taiyuan 030002, ChinaSchool of Traditional Chinese Medicine and Food Engineering, Shanxi University of Chinese Medicine,Jinzhong 030619, ChinaSchool of Traditional Chinese Medicine and Food Engineering, Shanxi University of Chinese Medicine,Jinzhong 030619, ChinaSchool of Nursing, Shanxi University of Traditional Chinese Medicine, Jinzhong 030619, ChinaObjective: To investigate the effects of Cerasus humilis composite rod on fatigue resistance and energy metabolism in mice. Methods: Fifty healthy male mice at 8 weeks of age were randomly divided into 5 groups: Control group, model group, Cerasus humilis composite rod group, positive group and high-fat group. By establishing a fatigue model of swimming+diet control, after 21 days of continuous feeding, the fatigue, energy metabolism and antioxidant related indexes of mice were detected by climbing poles and exhausting swimming time. Results: Compared with the control group, the climbing time and swimming time of the model group decreased significantly (P<0.01), the contents of lactate, blood urea nitrogen, creatine kinase and malondialdehyde were significantly increased (P<0.01), and serum superoxide dismutase, hepatic Na+-K+-ATPase and Ga2+-Mg2+-ATPase decreased significantly (P<0.05). Compared with the model group, the Cerasus humilis composite rod group and positive group could significantly prolong the time of climbing the pole and the time of swimming to exhaustion, which were 2.1 and 1.8 times that of the model group, and could effectively reduce energy consumption, reduce the accumulation of lactate and blood urea nitrogen (P<0.01, P<0.05), reduce the content of MDA and CK in serum, enhance the activity of SOD enzyme in serum (P<0.01), increase the activities of Na+-K+-ATPase and Ga2+-Mg2+-ATPase in liver (P<0.01), increase the level of ATP content and exert anti-fatigue activity. Conclusion: The composite rod has significant anti-fatigue ability and energy metabolism ability, which can improve the exercise ability level of mice by increasing the pole climbing time and weight-bearing exhaustion swimming time, and alleviate fatigue by reducing energy consumption, increasing energy metabolism, improving exercise endurance and improving antioxidant capacity.http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2023120121cerasus humiliscomposite rodanti-fatigueenergy metabolism |
| spellingShingle | Fangrong ZHANG Junmin DU Jianling KANG Wenying MAO Li BAI Caixing WANG Effects of Cerasus humilis Composite Rod on Anti-fatigue Capacity and Energy Metabolism in Mice Shipin gongye ke-ji cerasus humilis composite rod anti-fatigue energy metabolism |
| title | Effects of Cerasus humilis Composite Rod on Anti-fatigue Capacity and Energy Metabolism in Mice |
| title_full | Effects of Cerasus humilis Composite Rod on Anti-fatigue Capacity and Energy Metabolism in Mice |
| title_fullStr | Effects of Cerasus humilis Composite Rod on Anti-fatigue Capacity and Energy Metabolism in Mice |
| title_full_unstemmed | Effects of Cerasus humilis Composite Rod on Anti-fatigue Capacity and Energy Metabolism in Mice |
| title_short | Effects of Cerasus humilis Composite Rod on Anti-fatigue Capacity and Energy Metabolism in Mice |
| title_sort | effects of cerasus humilis composite rod on anti fatigue capacity and energy metabolism in mice |
| topic | cerasus humilis composite rod anti-fatigue energy metabolism |
| url | http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2023120121 |
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