Predictive value of TP53 RNAscope® in situ hybridization and p53 immunohistochemistry for TP53 mutational status in canine diffuse large B-cell lymphoma

Predictive value of TP53 RNAscope® in situ hybridization and p53 immunohistochemistry for TP53 mutational status in canine diffuse large B-cell lymphoma

TP53 mutations are associated with short survival and poor treatment response in canine diffuse large B-cell lymphoma (cDLBCL). The expression of TP53 by RNAscope® in situ hybridization and p53 by immunohistochemistry (IHC) was investigated in 37 formalin-fixed paraffin-embedded cDLBCL, to assess th...

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Bibliographic Details
Main Authors: Greta Foiani, Luca Licenziato, Laura Marconato, Antonella Fanelli, Erica Melchiotti, Claudia Zanardello, Luca Aresu, Marta Vascellari
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Veterinary Quarterly
Subjects:
Canine diffuse large B-cell lymphoma
immunohistochemistry
in situ hybridization
mutation
p53
TP53
Online Access:https://www.tandfonline.com/doi/10.1080/01652176.2024.2403453
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