Letter to the Editor: Spatial proximity of tumor–immune interactions predicts patient outcome in hepatocellular carcinoma

Abstract We read with interest the study entitled "Spatial proximity of tumor-immune interactions predicts patient outcome in hepatocellular "in Hepatology (Maestri E, Kedei N, Khatib S, et al. in Hepatology 79(4):768–79, 2024). This study utilized highly multiplexed CODEX imaging to compr...

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Main Authors: Gaoyao Peng, Jiangfa Li, Xinchou Wang
Format: Article
Language:English
Published: Springer 2024-12-01
Series:Discover Oncology
Online Access:https://doi.org/10.1007/s12672-024-01666-x
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author Gaoyao Peng
Jiangfa Li
Xinchou Wang
author_facet Gaoyao Peng
Jiangfa Li
Xinchou Wang
author_sort Gaoyao Peng
collection DOAJ
description Abstract We read with interest the study entitled "Spatial proximity of tumor-immune interactions predicts patient outcome in hepatocellular "in Hepatology (Maestri E, Kedei N, Khatib S, et al. in Hepatology 79(4):768–79, 2024). This study utilized highly multiplexed CODEX imaging to comprehensively analyze the spatial interactions between tumor and immune cells in hepatocellular carcinoma (HCC), yielding several meaningful findings and innovatively proposing the concept of the spatial neighborhood of immune cell infiltration and confirming its association with patient prognosis. After reading the article carefully, we have some suggestions to point out.
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institution Kabale University
issn 2730-6011
language English
publishDate 2024-12-01
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series Discover Oncology
spelling doaj-art-cf172b86419f4ae5a3ceec0165bf69722024-12-22T12:35:27ZengSpringerDiscover Oncology2730-60112024-12-011511210.1007/s12672-024-01666-xLetter to the Editor: Spatial proximity of tumor–immune interactions predicts patient outcome in hepatocellular carcinomaGaoyao Peng0Jiangfa Li1Xinchou Wang2Department of Breast Surgery, Guilin Women’s and Children’s HospitalDepartment of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guilin Medical University, Xiufen DistrictDepartment of Breast Surgery, Guilin Women’s and Children’s HospitalAbstract We read with interest the study entitled "Spatial proximity of tumor-immune interactions predicts patient outcome in hepatocellular "in Hepatology (Maestri E, Kedei N, Khatib S, et al. in Hepatology 79(4):768–79, 2024). This study utilized highly multiplexed CODEX imaging to comprehensively analyze the spatial interactions between tumor and immune cells in hepatocellular carcinoma (HCC), yielding several meaningful findings and innovatively proposing the concept of the spatial neighborhood of immune cell infiltration and confirming its association with patient prognosis. After reading the article carefully, we have some suggestions to point out.https://doi.org/10.1007/s12672-024-01666-x
spellingShingle Gaoyao Peng
Jiangfa Li
Xinchou Wang
Letter to the Editor: Spatial proximity of tumor–immune interactions predicts patient outcome in hepatocellular carcinoma
Discover Oncology
title Letter to the Editor: Spatial proximity of tumor–immune interactions predicts patient outcome in hepatocellular carcinoma
title_full Letter to the Editor: Spatial proximity of tumor–immune interactions predicts patient outcome in hepatocellular carcinoma
title_fullStr Letter to the Editor: Spatial proximity of tumor–immune interactions predicts patient outcome in hepatocellular carcinoma
title_full_unstemmed Letter to the Editor: Spatial proximity of tumor–immune interactions predicts patient outcome in hepatocellular carcinoma
title_short Letter to the Editor: Spatial proximity of tumor–immune interactions predicts patient outcome in hepatocellular carcinoma
title_sort letter to the editor spatial proximity of tumor immune interactions predicts patient outcome in hepatocellular carcinoma
url https://doi.org/10.1007/s12672-024-01666-x
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AT jiangfali lettertotheeditorspatialproximityoftumorimmuneinteractionspredictspatientoutcomeinhepatocellularcarcinoma
AT xinchouwang lettertotheeditorspatialproximityoftumorimmuneinteractionspredictspatientoutcomeinhepatocellularcarcinoma