Treatment of cutaneous Rosai-Dorfman disease with ALA-PDT combined with low-dose oral corticosteroids: A case report

Cutaneous Rosai-Dorfman Disease (CRDD), a rare form of Rosai-Dorfman Disease (RDD), lacks established treatment guidelines. In this case report, we detailed a successful case of CRDD management in a 50-year-old woman with facial lesions. Our treatment included 5-aminolevulinic acid photodynamic ther...

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Main Authors: Runke Zhou, Tingting Wang, Erlong Li, Li Li
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Photodiagnosis and Photodynamic Therapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1572100023006415
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author Runke Zhou
Tingting Wang
Erlong Li
Li Li
author_facet Runke Zhou
Tingting Wang
Erlong Li
Li Li
author_sort Runke Zhou
collection DOAJ
description Cutaneous Rosai-Dorfman Disease (CRDD), a rare form of Rosai-Dorfman Disease (RDD), lacks established treatment guidelines. In this case report, we detailed a successful case of CRDD management in a 50-year-old woman with facial lesions. Our treatment included 5-aminolevulinic acid photodynamic therapy (ALA-PDT) and low-dose oral corticosteroids. Remarkable improvement was evident after six ALA-PDT courses, and a one-year follow-up confirmed sustained remission. This case highlights the potential of combining ALA-PDT with low-dose corticosteroids as a promising therapeutic strategy for CRDD. Further research is necessary to fully elucidate its mechanisms and effectiveness.
format Article
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institution Kabale University
issn 1572-1000
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publishDate 2024-02-01
publisher Elsevier
record_format Article
series Photodiagnosis and Photodynamic Therapy
spelling doaj-art-cf13862fe22f447eb14898856e626cf62024-12-11T05:55:17ZengElsevierPhotodiagnosis and Photodynamic Therapy1572-10002024-02-0145103914Treatment of cutaneous Rosai-Dorfman disease with ALA-PDT combined with low-dose oral corticosteroids: A case reportRunke Zhou0Tingting Wang1Erlong Li2Li Li3Department of Dermatology, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Dermatology, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Dermatology, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Dermatology, West China Hospital, Sichuan University, Chengdu, China; Cosmetics Safety and Efficacy Evaluation Center, West China Hospital, Sichuan University, Chengdu, China; NMPA Key Laboratory for Human Evaluation and Big Data of Cosmetics, Chengdu, China; Corresponding author at: Department of Dermatology, West China Hospital, Sichuan University, Chengdu, China.Cutaneous Rosai-Dorfman Disease (CRDD), a rare form of Rosai-Dorfman Disease (RDD), lacks established treatment guidelines. In this case report, we detailed a successful case of CRDD management in a 50-year-old woman with facial lesions. Our treatment included 5-aminolevulinic acid photodynamic therapy (ALA-PDT) and low-dose oral corticosteroids. Remarkable improvement was evident after six ALA-PDT courses, and a one-year follow-up confirmed sustained remission. This case highlights the potential of combining ALA-PDT with low-dose corticosteroids as a promising therapeutic strategy for CRDD. Further research is necessary to fully elucidate its mechanisms and effectiveness.http://www.sciencedirect.com/science/article/pii/S1572100023006415Rosai-Dorfman diseaseRDDALA-PDTCorticosteroidPhotodynamic Therapy
spellingShingle Runke Zhou
Tingting Wang
Erlong Li
Li Li
Treatment of cutaneous Rosai-Dorfman disease with ALA-PDT combined with low-dose oral corticosteroids: A case report
Photodiagnosis and Photodynamic Therapy
Rosai-Dorfman disease
RDD
ALA-PDT
Corticosteroid
Photodynamic Therapy
title Treatment of cutaneous Rosai-Dorfman disease with ALA-PDT combined with low-dose oral corticosteroids: A case report
title_full Treatment of cutaneous Rosai-Dorfman disease with ALA-PDT combined with low-dose oral corticosteroids: A case report
title_fullStr Treatment of cutaneous Rosai-Dorfman disease with ALA-PDT combined with low-dose oral corticosteroids: A case report
title_full_unstemmed Treatment of cutaneous Rosai-Dorfman disease with ALA-PDT combined with low-dose oral corticosteroids: A case report
title_short Treatment of cutaneous Rosai-Dorfman disease with ALA-PDT combined with low-dose oral corticosteroids: A case report
title_sort treatment of cutaneous rosai dorfman disease with ala pdt combined with low dose oral corticosteroids a case report
topic Rosai-Dorfman disease
RDD
ALA-PDT
Corticosteroid
Photodynamic Therapy
url http://www.sciencedirect.com/science/article/pii/S1572100023006415
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AT tingtingwang treatmentofcutaneousrosaidorfmandiseasewithalapdtcombinedwithlowdoseoralcorticosteroidsacasereport
AT erlongli treatmentofcutaneousrosaidorfmandiseasewithalapdtcombinedwithlowdoseoralcorticosteroidsacasereport
AT lili treatmentofcutaneousrosaidorfmandiseasewithalapdtcombinedwithlowdoseoralcorticosteroidsacasereport