SAHA inhibits lung fibroblast activation by increasing p66Shc expression epigenetically
Abstract Objectives To investigate the effects of suberoylanilide hydroxamic acid (SAHA) on lung fibroblast activation and to examine the role of p66Shc in this process. Methods An in vitro pulmonary fibrosis model was established using transforming growth factor‐β (TGF‐β)‐induced MRC‐5 lung fibrobl...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-12-01
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| Series: | Aging Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/agm2.12385 |
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