Ecological safety of insecticide based on entomopathogenic virus DsCPV-1 for nontarget invertebrates

Abstract For the first time under laboratory conditions, the virulence of a unique cypovirus strain, DsCPV-1, which has broad host specificity, was tested on nontarget aquatic organisms (natural species: Gammarus lacustris, Anopheles messeae, Coenagrion lunulatum, Cloeon robusta, Chironomus sp., Ily...

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Main Authors: Olga Belevitch, Yuri Yurchenko, Daria Kharlamova, Elena Shatalova, Natalia Agrikolyanskaya, Anna Subbotina, Anastasia Ignatieva, Yuri Tokarev, Vyacheslav Martemyanov
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-024-78471-7
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author Olga Belevitch
Yuri Yurchenko
Daria Kharlamova
Elena Shatalova
Natalia Agrikolyanskaya
Anna Subbotina
Anastasia Ignatieva
Yuri Tokarev
Vyacheslav Martemyanov
author_facet Olga Belevitch
Yuri Yurchenko
Daria Kharlamova
Elena Shatalova
Natalia Agrikolyanskaya
Anna Subbotina
Anastasia Ignatieva
Yuri Tokarev
Vyacheslav Martemyanov
author_sort Olga Belevitch
collection DOAJ
description Abstract For the first time under laboratory conditions, the virulence of a unique cypovirus strain, DsCPV-1, which has broad host specificity, was tested on nontarget aquatic organisms (natural species: Gammarus lacustris, Anopheles messeae, Coenagrion lunulatum, Cloeon robusta, Chironomus sp., Ilyocoris cimicoides, and Plea minutissima; laboratory species: Aedes aegypti and Daphnia magna), a terrestrial pollinator species (Apis mellifera), and an entomophage (Podisus maculiventris). The probability of this virus’s accumulation in the bodies of invertebrates and of its transmission along a trophic chain was evaluated by two approaches: bioassays and a molecular diagnostic analysis. In the bioassays, there was no significant increase in mortality among all the tested aquatic and terrestrial nontarget species exposed to DsCPV-1 as compared with control groups (no virus). When we fed Podisus maculiventris with caterpillars having active DsCPV-1 infection (i.e., with the virus replicating in the host) no viral replication was observed in bug. No replication was also observed in mosquitos as well as in bee after viral treatment. Thus, the results show that the DsCPV-1 virus has excellent environmental safety toward many invertebrate species and can be recommended for the control of lepidopteran pests in forestry and agriculture as insecticide with light effect on environment.
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spelling doaj-art-ced3bd80cac7416bbc4dba13a40b6aff2024-11-24T12:24:21ZengNature PortfolioScientific Reports2045-23222024-11-0114111010.1038/s41598-024-78471-7Ecological safety of insecticide based on entomopathogenic virus DsCPV-1 for nontarget invertebratesOlga Belevitch0Yuri Yurchenko1Daria Kharlamova2Elena Shatalova3Natalia Agrikolyanskaya4Anna Subbotina5Anastasia Ignatieva6Yuri Tokarev7Vyacheslav Martemyanov8Institute of Systematics and Ecology of Animals SB RASInstitute of Systematics and Ecology of Animals SB RASInstitute of Systematics and Ecology of Animals SB RASSiberian Federal Scientific Centre of Agrobiotechnologies of the Russian Academy of Sciences (SFSCA RAS)Siberian Federal Scientific Centre of Agrobiotechnologies of the Russian Academy of Sciences (SFSCA RAS)Institute of Systematics and Ecology of Animals SB RASAll-Russian Institute of Plant ProtectionAll-Russian Institute of Plant ProtectionInstitute of Systematics and Ecology of Animals SB RASAbstract For the first time under laboratory conditions, the virulence of a unique cypovirus strain, DsCPV-1, which has broad host specificity, was tested on nontarget aquatic organisms (natural species: Gammarus lacustris, Anopheles messeae, Coenagrion lunulatum, Cloeon robusta, Chironomus sp., Ilyocoris cimicoides, and Plea minutissima; laboratory species: Aedes aegypti and Daphnia magna), a terrestrial pollinator species (Apis mellifera), and an entomophage (Podisus maculiventris). The probability of this virus’s accumulation in the bodies of invertebrates and of its transmission along a trophic chain was evaluated by two approaches: bioassays and a molecular diagnostic analysis. In the bioassays, there was no significant increase in mortality among all the tested aquatic and terrestrial nontarget species exposed to DsCPV-1 as compared with control groups (no virus). When we fed Podisus maculiventris with caterpillars having active DsCPV-1 infection (i.e., with the virus replicating in the host) no viral replication was observed in bug. No replication was also observed in mosquitos as well as in bee after viral treatment. Thus, the results show that the DsCPV-1 virus has excellent environmental safety toward many invertebrate species and can be recommended for the control of lepidopteran pests in forestry and agriculture as insecticide with light effect on environment.https://doi.org/10.1038/s41598-024-78471-7HydrobiontPollinatorEntomophageHoney beeEcologically friendly bioinsecticideGreen technology
spellingShingle Olga Belevitch
Yuri Yurchenko
Daria Kharlamova
Elena Shatalova
Natalia Agrikolyanskaya
Anna Subbotina
Anastasia Ignatieva
Yuri Tokarev
Vyacheslav Martemyanov
Ecological safety of insecticide based on entomopathogenic virus DsCPV-1 for nontarget invertebrates
Scientific Reports
Hydrobiont
Pollinator
Entomophage
Honey bee
Ecologically friendly bioinsecticide
Green technology
title Ecological safety of insecticide based on entomopathogenic virus DsCPV-1 for nontarget invertebrates
title_full Ecological safety of insecticide based on entomopathogenic virus DsCPV-1 for nontarget invertebrates
title_fullStr Ecological safety of insecticide based on entomopathogenic virus DsCPV-1 for nontarget invertebrates
title_full_unstemmed Ecological safety of insecticide based on entomopathogenic virus DsCPV-1 for nontarget invertebrates
title_short Ecological safety of insecticide based on entomopathogenic virus DsCPV-1 for nontarget invertebrates
title_sort ecological safety of insecticide based on entomopathogenic virus dscpv 1 for nontarget invertebrates
topic Hydrobiont
Pollinator
Entomophage
Honey bee
Ecologically friendly bioinsecticide
Green technology
url https://doi.org/10.1038/s41598-024-78471-7
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